SCHEMBL4338569

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4336796	0.86	GSK3B (0.49)	GSK3BMAPK14
	SCHEMBL4334983	0.83	MAPK10 (0.49)	ADORA3ADORA2AADORA1ALDH1A1KDM4E
	SCHEMBL4335335	0.80	MEN1 (0.48)	SMN1; SMN2MEN1KMT2APOLBGSK3B
	SCHEMBL4336464	0.78	ADORA3 (0.47)	ADORA3ADORA2AADORA1ALDH1A1KDM4E
	SCHEMBL4329234	0.76	MAPT (0.44)	ADORA3ADORA2AADORA1ALDH1A1KDM4E
	SCHEMBL2861587	0.74	KDR (0.49)	NPC1RAB9AGSK3B
	SCHEMBL2861507	0.74	TTK (0.47)	ALDH1A1KDM4ELMNASMN1; SMN2NPC1
	SCHEMBL4335978	0.72	GSK3B (0.47)	ALDH1A1HDAC1HDAC2HTTGSK3B
	SCHEMBL4338883	0.72	GSK3B (0.58)	ADORA3ADORA2AADORA1GSK3B
	SCHEMBL2870195	0.72	MAP2K4 (0.43)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.