Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | BID | P55957 | 3/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.33 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4341943 | 0.97 | SOAT2 (0.38) | SOAT2SOAT1PPARGPPARAFAAH | |
| SCHEMBL4341891 | 0.95 | EPHX2 (0.39) | SOAT2SOAT1CYP3A4TSHRPPARG | |
| SCHEMBL4341910 | 0.92 | EPHX2 (0.35) | SOAT2SOAT1CYP3A4TSHRPPARG | |
| SCHEMBL4333096 | 0.92 | EPHX2 (0.35) | SOAT2SOAT1CYP3A4TSHRPPARG | |
| SCHEMBL4337716 | 0.92 | EPHX2 (0.35) | SOAT2SOAT1CYP3A4TSHRPPARG | |
| SCHEMBL4344025 | 0.87 | EPHX2 (0.35) | SOAT2SOAT1CYP3A4TSHRPPARG | |
| SCHEMBL702655 | 0.80 | PRSS1 (0.33) | — | |
| SCHEMBL15643948 | 0.80 | PTGS2 (0.30) | PTGS2 | |
| SCHEMBL706845 | 0.77 | KCNH2 (0.33) | CYP3A4TSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2481870 | 0.76 | CYSLTR2 (0.32) | CYP3A4CYSLTR2CYSLTR1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133686-A1 | MEDICAMENTS FOR TREATING ALZHEIMER'S DISEASE | 有限会社アンティアンティ (JP) | 2009-11-05 | — | — | WO | disclosed |