Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | F7 | P08709 | 2/20 | 0.33 |
| ▸ | F3 | P13726 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4341910 | 1.00 | EPHX2 (0.35) | EPHX2FAAHCNR1CNR2ALDH1A1 | |
| SCHEMBL4333096 | 1.00 | EPHX2 (0.35) | EPHX2FAAHCNR1CNR2ALDH1A1 | |
| SCHEMBL4344025 | 0.95 | EPHX2 (0.35) | EPHX2FAAHCNR1CNR2ALDH1A1 | |
| SCHEMBL4335115 | 0.92 | SOAT2 (0.35) | EPHX2FAAHCNR1CNR2MAPT | |
| SCHEMBL4341943 | 0.92 | SOAT2 (0.38) | EPHX2FAAHCNR1CNR2PPARG | |
| SCHEMBL4341891 | 0.90 | EPHX2 (0.39) | EPHX2FAAHCNR1CNR2ALDH1A1 | |
| SCHEMBL15643948 | 0.80 | PTGS2 (0.30) | PTGS2 | |
| SCHEMBL702655 | 0.77 | PRSS1 (0.33) | — | |
| SCHEMBL706845 | 0.77 | KCNH2 (0.33) | ALDH1A1CYP3A4MEN1LMNAKMT2A | |
| SCHEMBL2481870 | 0.76 | CYSLTR2 (0.32) | ALDH1A1MAPTCYP3A4ALOX15MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133686-A1 | MEDICAMENTS FOR TREATING ALZHEIMER'S DISEASE | 有限会社アンティアンティ (JP) | 2009-11-05 | — | — | WO | disclosed |