Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9647822 | 0.98 | TDP1 (0.69) | TDP1POLBAPEX1HTTLMNA | |
| SCHEMBL28351135 | 0.98 | TDP1 (0.69) | TDP1POLBAPEX1HTTLMNA | |
| SCHEMBL10790604 | 0.98 | TDP1 (0.69) | TDP1POLBAPEX1HTTLMNA | |
| SCHEMBL9647846 | 0.98 | TDP1 (0.69) | TDP1POLBAPEX1HTTLMNA | |
| SCHEMBL435195 | 0.97 | TDP1 (0.66) | TDP1POLBAPEX1HTTLMNA | |
| SCHEMBL436276 | 0.93 | LMNA (0.61) | TDP1POLBAPEX1HTTLMNA | |
| SCHEMBL29316022 | 0.91 | TDP1 (0.58) | TDP1POLBAPEX1HTTLMNA | |
| SCHEMBL29316026 | 0.90 | TDP1 (0.59) | TDP1POLBAPEX1HTTLMNA | |
| SCHEMBL29316023 | 0.90 | TDP1 (0.59) | TDP1POLBAPEX1HTTLMNA | |
| Dimethylamine SCHEMBL1021289 | 0.89 | LMNA (0.56) | TDP1POLBAPEX1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012010918-A2 | OPTICAL DEVICES | MEDICONTUR ORVOSTECHNIKAI KFT. (HU) | 2012-01-26 | — | — | WO | disclosed |
| EP-0313474-B1 | AN OPTICAL ARTICLE EXHIBITING A HIGH LEVEL OF SECOND ORDER POLARIZATION SUSCEPTIBILITY | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1992-12-23 | — | — | EP | disclosed |
| EP-0313475-B1 | AN OPTICAL ARTICLE CONTAINING A TRANSMISSION MEDIUM EXHIBITING A HIGH LEVEL OF SECOND ORDER POLARIZATION SUSCEPTIBILITY | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1992-12-23 | — | — | EP | disclosed |
| EP-0313476-B1 | AN OPTICAL ARTICLE CONTAINING A POLYMERIC MATRIX EXHIBITING A HIGH LEVEL OF SECOND ORDER POLARIZATION SUSCEPTIBILITY | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1992-12-23 | — | — | EP | disclosed |
| US-4886339-A | MOLECULAR DIPOLES HELD IN POLAR ALIGNMENT BY A CROSSLINKED POLYMERIC BINDER; STABILITY | EASTMAN KODAK COMPANY (US) | 1989-12-12 | — | — | US | disclosed |
| EP-0313474-A2 | An optical article exhibiting a high level of second order polarization susceptibility | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-04-26 | — | — | EP | disclosed |
| EP-0313475-A2 | An optical article containing a transmission medium exhibiting a high level of second order polarization susceptibility | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-04-26 | — | — | EP | disclosed |
| EP-0313476-A2 | An optical article containing a polymeric matrix exhibiting a high level of second order polarization susceptibility | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-04-26 | — | — | EP | disclosed |
| US-4796971-A | CHARGE TRANSFER COMPOUND ON CROSSLINKED MATRIX | EASTMAN KODAK COMPANY (US) | 1989-01-10 | — | — | US | disclosed |
| US-4792208-A | POLAR ALIGNED NONCENTROSYMMETRIC MOLECULAR DIPOLES; SULFONYL MOIETY AS ELECTRON ACCEPTOR | EASTMAN KODAK COMPANY (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0129234-A1 | Electrophotographic elements having barrier layers of crosslinked polymers | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1984-12-27 | — | — | EP | disclosed |
| US-4485161-A | Electrophotographic elements having barrier layers of crosslinked polymers of aliphatic or aromatic monomers containing α,β-ethylenically unsaturated carbonyl-containing substituents | EASTMAN KODAK COMPANY (US) | 1984-11-27 | — | — | US | disclosed |
| US-4322490-A | Photopolymerizable compositions featuring improved monomers | EASTMAN KODAK COMPANY (US) | 1982-03-30 | — | — | US | disclosed |