SCHEMBL4336157

SCHEMBL4336157

CC1(C)CCCC(C)(C)N1OC(=O)CCCC(=O)ON1C(C)(C)CCCC1(C)C

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
GAA P10253 1/20 0.38
TSHR P16473 3/20 0.37
NFKB1 P19838 1/20 0.35
CYP2C19 P33261 1/20 0.35
NAAA Q02083 1/20 0.32
GLA P06280 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6013601 0.96 KMT2A (0.38) KMT2AMEN1GAATSHRNFKB1
SCHEMBL194968 0.94 NAAA (0.38) KMT2AMEN1GAATSHRNFKB1
SCHEMBL195275 0.92 TSHR (0.37) KMT2AMEN1GAATSHRNFKB1
SCHEMBL30992149 0.90 KMT2A (0.38) KMT2AMEN1GAATSHRNFKB1
SCHEMBL4341466 0.88 NAAA (0.47) KMT2AMEN1TSHRNAAALMNA
SCHEMBL15902712 0.88 NAAA (0.47) KMT2AMEN1TSHRNAAALMNA
SCHEMBL716439 0.88 TSHR (0.39) KMT2AMEN1TSHRNFKB1LMNA
SCHEMBL6889651 0.88 NAAA (0.47) KMT2AMEN1TSHRNAAALMNA
SCHEMBL4014755 0.88 NAAA (0.47) KMT2AMEN1TSHRNAAALMNA
SCHEMBL3632253 0.85 LMNA (0.39) KMT2AMEN1GAATSHRNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090054565-A1 Flame-Retardant plastics molding composition CLARIANT INTERNATIONAL LTD. 2009-02-26 US disclosed
US-6013706-A Process for the preparation of hyrolysis-stable trivalent phosphorus compounds and their use as stabilizers for thermoplastics CLARIANT GMBH (DE) 2000-01-11 US disclosed
US-5852159-A Plastic with reduced sulfur uptake rate HOECHST AKTIENGESELLSCHAFT (DE) 1998-12-22 US disclosed
US-5633378-A STABILIZER FOR POLYMERS HOECHST AKTIENGESELLSCHAFT (DE) 1997-05-27 US disclosed
US-5594142-A USING SOLVENT MIXTURE AND BASIC CATALYST HOECHST AKTIENGESELLSCHAFT (DE) 1997-01-14 US disclosed
US-5550242-A REACTION CARRIED OUT IN INERT ORGANIC SOLVENT IN PRESENCE OF SOLID ALKALI METAL HYDROXIDE OR A MIXTURE OF HYDROXIDE AND WATER; AVOIDS USE OF PHASE TRANSFER CATALYST HOECHST AKTIENGESELLSCHAFT (DE) 1996-08-27 US disclosed
US-5550234-A STABILIZERS WITH VERY LOW VOLATILITY AT ELEVATED TEMPERATURES HOECHST AKTIENGESELLSCHAFT (DE) 1996-08-27 US disclosed
US-5331034-A Deactivation of catalyst residues with ditrimethylolpropane HOECHST AKTIENGESELLSCHAFT (DE) 1994-07-19 US disclosed
US-5326805-A Flame-retardant plastics molding composition of improved stability HOECHST AKTIENGESELLSCHAFT (DE) 1994-07-05 US disclosed
US-5298541-A Molding materials HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-29 US disclosed
US-5169925-A Light stabilizers for polymers; photooxidation resistance; nondestructive; nondiffusing; heat resistance; molding materials HOECHST AKTIENGESELLSCHAFT (DE) 1992-12-08 US disclosed