SCHEMBL3632253

SCHEMBL3632253

CC1(C)CCCC(C)(C)N1OC(=O)CCC(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.39
EGLN1 Q9GZT9 2/20 0.37
KDM6B O15054 1/20 0.37
KDM5C P41229 1/20 0.37
PHF8 Q9UPP1 1/20 0.37
KDM2A Q9Y2K7 1/20 0.37
TSHR P16473 2/20 0.37
NFKB1 P19838 1/20 0.37
CYP2C19 P33261 1/20 0.37
ALKBH5 Q6P6C2 1/20 0.32
SUCNR1 Q9BXA5 1/20 0.32
ALDH1A1 P00352 2/20 0.32
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP1A2 P05177 1/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
SLC15A2 Q16348 1/20 0.31
UGT2B7 P16662 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL195275 0.93 TSHR (0.37) TSHRNFKB1CYP2C19MEN1GAA
SCHEMBL27403917 0.90 TSHR (0.40) LMNATSHRNFKB1CYP2C19ALDH1A1
SCHEMBL716439 0.88 TSHR (0.39) LMNATSHRNFKB1ALDH1A1MEN1
SCHEMBL6013601 0.85 KMT2A (0.38) LMNATSHRNFKB1CYP2C19ALDH1A1
SCHEMBL4336157 0.85 KMT2A (0.38) LMNATSHRNFKB1CYP2C19MEN1
SCHEMBL194968 0.84 NAAA (0.38) LMNATSHRNFKB1CYP2C19ALDH1A1
SCHEMBL28288158 0.84 NAAA (0.38) LMNATSHRNFKB1CYP2C19ALDH1A1
SCHEMBL27703376 0.84 NAAA (0.38) LMNATSHRNFKB1CYP2C19ALDH1A1
SCHEMBL8308600 0.81 TSHR (0.37) TSHRNFKB1CYP2C19MEN1GAA
SCHEMBL30992149 0.79 KMT2A (0.38) LMNATSHRNFKB1CYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11111358-B2 Stabilizer compounds SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2021-09-07 US disclosed
US-11111215-B2 Piperidine-based stabilizers and polymers end-capped with the same SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2021-09-07 US disclosed
US-10954359-B2 Hydroxybenzophenone-based stabilizers and polymers end-capped with the same SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2021-03-23 US disclosed
CN-106458895-B Piperidine-based stabilizers and polymers capped therewith 索尔维特殊聚合物美国有限责任公司 2020-12-11 CN disclosed
EP-3145911-B1 STABILIZER COMPOUNDS SOLVAY SPECIALTY POLYMERS USA L L C (US) 2020-07-08 EP disclosed
US-20200157312-A1 STABILIZER COMPOUNDS SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2020-05-21 US disclosed
US-20200115340-A1 PIPERIDINE-BASED STABILIZERS AND POLYMERS END-CAPPED WITH THE SAME SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2020-04-16 US disclosed
US-20190338105-A1 Hydroxybenzophenone-based stabilizers and polymers end-capped with the same SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2019-11-07 US disclosed
US-10400087-B2 Hydroxybenzophenone-based stabilizers and polymers end-capped with the same SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2019-09-03 US disclosed
EP-3145910-B1 PIPERIDINE-BASED STABILIZERS AND POLYMERS END-CAPPED WITH THE SAME SOLVAY SPECIALTY POLYMERS USA (US) 2018-07-11 EP disclosed
CN-101910270-B Gamma radiation sterilizable, reinforced polymer compositions with improved color stability SOLVAY ADVANCED POLYMERS LLC 2014-11-26 CN disclosed
CN-102093282-B Oxime ester photoinitiators CIBA SC HOLDING AG 2014-02-12 CN disclosed
US-8524821-B2 Gamma radiation sterilizable, reinforced polymer composition with improved color stability SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2013-09-03 US disclosed
CN-101014569-B Oxime ester photoinitiators CIBA SC HOLDING AG 2013-01-02 CN disclosed
CN-101203556-B Stabiliser composition for chlorine-containing polymers SUN ACE KAKOH PTE LTD 2012-06-27 CN disclosed
US-20100262142-A1 Gamma radiation sterilizable, reinforced polymer composition with improved color stability SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2010-10-14 US disclosed
CN-101203556-A Stabiliser composition for chlorine-containing polymers SUN ACE KAKOH PTE LTD (SG) 2008-06-18 CN disclosed
US-7255814-B2 Flame retardant and stabilizer combined for thermoplastics polymers CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2007-08-14 US disclosed
US-20040227130-A1 Flame retardant and stabilizer combined for thermoplastics polymers CLARIANT GMBH 2004-11-18 US disclosed
CN-1143093-A Sulphur absorption speed reduced plastic HOECHST AG (DE) 1997-02-19 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200157312-A1 STABILIZER COMPOUNDS HSF1, HEATR1, TBCA LMNA 1511/4885EGLN1 540/4885KDM6B 2094/4885
US-20190338105-A1 Hydroxybenzophenone-based stabilizers and polymers end-capped with the same TYR, HSPA1B, HSPH1 LMNA 2872/4885EGLN1 454/4885KDM6B 656/4885
US-10954359-B2 Hydroxybenzophenone-based stabilizers and polymers end-capped with the same TYR, HSPA1B, HSPH1 LMNA 2872/4885EGLN1 454/4885KDM6B 656/4885
US-10400087-B2 Hydroxybenzophenone-based stabilizers and polymers end-capped with the same TYR, HAO2, UNG LMNA 2813/4885EGLN1 387/4885KDM6B 509/4885
US-20200115340-A1 PIPERIDINE-BASED STABILIZERS AND POLYMERS END-CAPPED WITH THE SAME CAPZA1, UNG, CAPZA2 LMNA 1895/4885EGLN1 450/4885KDM6B 1199/4885
US-11111358-B2 Stabilizer compounds HSF1, HEATR1, TBCA LMNA 1511/4885EGLN1 540/4885KDM6B 2094/4885
US-11111215-B2 Piperidine-based stabilizers and polymers end-capped with the same CAPZA1, UNG, CAPZA2 LMNA 1895/4885EGLN1 450/4885KDM6B 1199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.