SCHEMBL433656

SCHEMBL433656

NCCCCC(NCC(O)CCN)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.49
GSR P00390 1/20 0.44
RNPEP Q9H4A4 1/20 0.43
MMP2 P08253 1/20 0.40
MMP9 P14780 1/20 0.40
GGT1 P19440 1/20 0.40
CPB2 Q96IY4 10/20 0.40
SLC6A5 Q9Y345 1/20 0.39
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
TLR2 O60603 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2117551 1.00 FOLH1 (0.49) FOLH1GSRRNPEPMMP2MMP9
SCHEMBL433657 1.00 FOLH1 (0.49) FOLH1GSRRNPEPMMP2MMP9
SCHEMBL30540130 0.93 FOLH1 (0.49) FOLH1GSRRNPEPMMP2MMP9
SCHEMBL4087629 0.88 FOLH1 (0.47) FOLH1GSRRNPEPMMP2MMP9
SCHEMBL4100264 0.88 FOLH1 (0.47) FOLH1GSRRNPEPMMP2MMP9
Hydrochloric Acid SCHEMBL6010125 0.87 FOLH1 (0.46) FOLH1GSRRNPEPMMP2MMP9
Hydrochloric Acid SCHEMBL6010135 0.87 FOLH1 (0.46) FOLH1GSRRNPEPMMP2MMP9
SCHEMBL28450260 0.86 SLC6A5 (0.52) FOLH1SLC6A5TLR2
SCHEMBL9924207 0.85 FOLH1 (0.45) FOLH1GSRRNPEPMMP2MMP9
SCHEMBL6010377 0.83 FOLH1 (0.41) FOLH1GSRRNPEPMMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260043042-A1 Plants with Modified Deoxyhypusine Synthase Genes AGRIBODY TECHNOLOGIES, INC. (US) 2026-02-12 US disclosed
US-20240366738-A1 MOLECULAR VACCINES FOR INFECTIOUS DISEASE AGILENT TECHNOLOGIES INC (US) 2024-11-07 US disclosed
US-20240188521-A1 Plants with Modified Deoxyhypusine Synthase Genes AGRIBODY TECHNOLOGIES, INC. (US) 2024-06-13 US disclosed
US-11992518-B2 Molecular vaccines for infectious disease AGILENT TECHNOLOGIES, INC. (US) 2024-05-28 US disclosed
WO-2024011167-A2 PLANTS WITH MODIFIED DEOXYHYPUSINE SYNTHASE GENES AGRIBODY TECHNOLOGIES, INC. (US) 2024-01-11 WO disclosed
US-10973187-B2 Plants with modified deoxyhypusine synthase genes AGRIBODY TECHNOLOGIES, INC. (US) 2021-04-13 US disclosed
US-10968269-B1 MHC multimers in borrelia diagnostics and disease AGILENT TECHNOLOGIES, INC. (US) 2021-04-06 US disclosed
US-20210047383-A1 MHC Multimers in Borrelia Diagnostics and Disease DAKO DENMARK APS (DK) 2021-02-18 US disclosed
US-20200347103-A1 MHC MULTIMERS IN TUBERCULOSIS DIAGNOSTICS, VACCINE AND THERAPEUTICS AGILENT TECHNOLOGIES INC (US) 2020-11-05 US disclosed
EP-3731626-A1 PLANTS WITH MODIFIED DHS GENES Agribody Technologies, Inc. (US) 2020-11-04 EP disclosed
US-20030101488-A1 DNA encoding a plant deoxyhypusine synthase, a plant eukaryotic initiation factor 5A, transgenic plants and a method for controlling senescence programmed and cell death in plants SENESCO, INC. 2003-05-29 US disclosed
US-6538182-B1 Genetic modification of plants to control age-related or environmental stress-induced senescence; use in extending shelf-life and slowing spoilage of plant cuttings, flowers, seeds, fruits, vegatables, or leaves SENESCO, INC. 2003-03-25 US disclosed
WO-2003018014-A2 METHODS OF INHIBITING FORMATION OF VASCULAR CHANNELS AND PROFILERATION USING PYRIDINONE DERIVATIVES THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2003-03-06 WO disclosed
WO-2002044392-A2 DNA ENCODING A PLANT DEOXYHYPUSINE SYNTHASE, A PLANT EUKARYOTIC INITIATION FACTOR 5A, TRANSGENIC PLANTS AND A METHOD FOR CONTROLLING SENESCENCE PROGRAMMED AND CELL DEATH IN PLANTS SENESCO TECHNOLOGIES, INC. (US) 2002-06-06 WO disclosed
EP-1200612-A2 DNA ENCODING A PLANT DEOXYHYPUSINE SYNTHASE, A PLANT EUKARYOTIC INITIATION FACTOR 5A, TRANSGENIC PLANTS AND A METHOD FOR CONTROLLING SENESCENCE AND PROGRAMMED CELL DEATH IN PLANTS Senesco, Inc. (US) 2002-05-02 EP disclosed
WO-2001002592-A9 DNA ENCODING A PLANT DEOXYHYPUSINE SYNTHASE, A PLANT EUKARYOTIC INITIATION FACTOR 5A, TRANSGENIC PLANTS AND A METHOD FOR CONTROLLING SENESCENCE AND PROGRAMMED CELL DEATH IN PLANTS SENESCO INC (US) 2001-08-02 WO disclosed
WO-2001002592-A2 DNA ENCODING A PLANT DEOXYHYPUSINE SYNTHASE, A PLANT EUKARYOTIC INITIATION FACTOR 5A, TRANSGENIC PLANTS AND A METHOD FOR CONTROLLING SENESCENCE AND PROGRAMMED CELL DEATH IN PLANTS SENESCO, INC. (US) 2001-01-11 WO disclosed
US-5670477-A Method to enhance permeability of the blood/brain blood/nerve bariers to therapeutic agents Poduslo, Joseph F. (US) 1997-09-23 US disclosed
WO-1994015596-A1 COMPOSITIONS AND METHODS FOR INHIBITING DEOXYHYPUSINE SYNTHASE AND THE GROWTH OF CELLS THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1994-07-21 WO disclosed
WO-1992005190-A1 DEOXYHYPUSYL HYDROXYLASE INHIBITORS THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 1992-04-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260043042-A1 Plants with Modified Deoxyhypusine Synthase Genes DHPS, FDPS, FPGS FOLH1 1966/4885GSR 788/4885RNPEP 1927/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.