Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.90 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.90 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.90 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4340745 | 0.93 | ALDH1A1 (0.97) | ALDH1A1KDM4ESMN1; SMN2KMT2AMAPT | |
| SCHEMBL12841607 | 0.85 | ALDH1A1 (0.71) | ALDH1A1KDM4ESMN1; SMN2KMT2AMAPT | |
| SCHEMBL12658282 | 0.85 | ALDH1A1 (0.71) | ALDH1A1KDM4ESMN1; SMN2KMT2AMAPT | |
| SCHEMBL12841719 | 0.83 | ALDH1A1 (0.74) | ALDH1A1KDM4ESMN1; SMN2KMT2AMAPT | |
| SCHEMBL12432242 | 0.82 | ALDH1A1 (0.68) | ALDH1A1KDM4ESMN1; SMN2KMT2AMAPT | |
| SCHEMBL12658438 | 0.82 | ALDH1A1 (0.68) | ALDH1A1KDM4ESMN1; SMN2KMT2AMAPT | |
| SCHEMBL12658437 | 0.82 | ALDH1A1 (0.68) | ALDH1A1KDM4ESMN1; SMN2KMT2AMAPT | |
| SCHEMBL4347038 | 0.82 | ALDH1A1 (0.68) | ALDH1A1KDM4ESMN1; SMN2KMT2AMAPT | |
| SCHEMBL12431236 | 0.82 | ALDH1A1 (0.67) | ALDH1A1KDM4ESMN1; SMN2KMT2AMAPT | |
| SCHEMBL14393763 | 0.80 | ALDH1A1 (0.64) | ALDH1A1KDM4ESMN1; SMN2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7611696-B2 | Sunscreen compositions as well as dihydropyridines and dihydropyranes | DSM IP ASSETS B.V. (NL) | 2009-11-03 | — | — | US | claimed |
| EP-1474098-B1 | SUNSCREEN COMPOSITIONS AS WELL AS DIHYDROPYRIDINES AND DIHYDROPYRANES | DSM IP ASSETS BV (NL) | 2006-08-02 | — | — | EP | claimed |
| US-20050019278-A1 | Sunscreen compositions as well as dihydropyridines and dihydropyranes | ROCHE VITAMINS AG (CH) | 2005-01-27 | — | — | US | claimed |
| EP-1474098-A1 | SUNSCREEN COMPOSITIONS AS WELL AS DIHYDROPYRIDINES AND DIHYDROPYRANES | DSM IP Assets B.V. (NL) | 2004-11-10 | — | — | EP | claimed |
| WO-2003068183-A1 | SUNSCREEN COMPOSITIONS AS WELL AS DIHYDROPYRIDINES AND DIHYDROPYRANES | DSM IP ASSETS B.V. (NL) | 2003-08-21 | — | — | WO | claimed |
| CN-100563622-C | Light screening composition and dihydropyridine and dihydropyran | DSM IP ASSETS BV (NL) | 2009-12-02 | — | — | CN | disclosed |
| US-7611696-B2 | Sunscreen compositions as well as dihydropyridines and dihydropyranes | DSM IP ASSETS B.V. (NL) | 2009-11-03 | — | — | US | disclosed |
| EP-1474098-B1 | SUNSCREEN COMPOSITIONS AS WELL AS DIHYDROPYRIDINES AND DIHYDROPYRANES | DSM IP ASSETS BV (NL) | 2006-08-02 | — | — | EP | disclosed |
| CN-1630504-A | Sunscreen compositions as well as dihydropyridines and dihydropyranes | DSM IP ASSETS BV (NL) | 2005-06-22 | — | — | CN | disclosed |
| US-20050019278-A1 | Sunscreen compositions as well as dihydropyridines and dihydropyranes | ROCHE VITAMINS AG (CH) | 2005-01-27 | — | — | US | disclosed |
| EP-1474098-A1 | SUNSCREEN COMPOSITIONS AS WELL AS DIHYDROPYRIDINES AND DIHYDROPYRANES | DSM IP Assets B.V. (NL) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003068183-A1 | SUNSCREEN COMPOSITIONS AS WELL AS DIHYDROPYRIDINES AND DIHYDROPYRANES | DSM IP ASSETS B.V. (NL) | 2003-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050019278-A1 | Sunscreen compositions as well as dihydropyridines and dihydropyranes | DHPS, DSG1, DHODH | ALDH1A1 154/4885KDM4E 1689/4885SMN1; SMN2 4037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.