Ethylene

Ethylene

SCHEMBL4332388

C1=CC([Hf](c2ccccc2)(c2ccccc2)C2C=Cc3ccccc32)c2ccccc21.C=C

nearest known ligand 0.33

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Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.33
HTR2A P28223 1/20 0.33
SIGMAR1 Q99720 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3381474 0.94 HTR2A (0.34) HTR6HTR2ASIGMAR1
Ethylene SCHEMBL9289285 0.77 HTR6 (0.39) HTR6HTR2A
Ethylene SCHEMBL4337188 0.77 HTR2A (0.35) HTR6HTR2ASIGMAR1
Hydrochloric Acid SCHEMBL7939818 0.76 HTR2A (0.36) HTR6HTR2ASIGMAR1
Hydrochloric Acid SCHEMBL7640033 0.76 HTR6 (0.33) HTR6HTR2ASIGMAR1
Hydrochloric Acid SCHEMBL10434700 0.76 SIGMAR1 (0.33) HTR6HTR2ASIGMAR1
Ethylene SCHEMBL4323027 0.73 HTR2A (0.36) HTR6HTR2ASIGMAR1
SCHEMBL3382688 0.72 HTR2A (0.38) HTR6HTR2ASIGMAR1
SCHEMBL3385243 0.72 HTR2A (0.38) HTR6HTR2ASIGMAR1
SCHEMBL8380950 0.72 HTR2A (0.38) HTR6HTR2ASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7592403-B2 Ethylene polymer, preparation process thereof and molded articles of the same MITSUI CHEMICALS, INC. (JP) 2009-09-22 US claimed
US-7592403-B2 Ethylene polymer, preparation process thereof and molded articles of the same MITSUI CHEMICALS, INC. (JP) 2009-09-22 US disclosed
US-20050267273-A1 Ethylene polymer, preparation process thereof and molded articles of the same MITSUI CHEMICALS, INC. 2005-12-01 US disclosed
EP-1231229-A2 Ethylene polymer, preparation process thereof and molded articles of the same Mitsui Chemicals, Inc. (JP) 2002-08-14 EP disclosed
US-20020107343-A1 Ethylene polymer, preparation process thereof and molded articles of the same MITSUI CHEMICALS, INC. 2002-08-08 US disclosed