Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9796637 | 0.89 | MGAM (0.34) | SMN1; SMN2CA1CA2MEN1KMT2A | |
| SCHEMBL6337130 | 0.80 | DPP4 (0.38) | SMN1; SMN2CA1CA2MEN1KMT2A | |
| SCHEMBL6337127 | 0.80 | DPP4 (0.38) | SMN1; SMN2CA1CA2MEN1KMT2A | |
| SCHEMBL7207341 | 0.78 | ALDH1A1 (0.37) | SMN1; SMN2KMT2ATSHR | |
| SCHEMBL9796657 | 0.75 | CA1 (0.40) | SMN1; SMN2CA1CA2MEN1KMT2A | |
| SCHEMBL10962327 | 0.73 | ALDH1A1 (0.32) | TSHR | |
| SCHEMBL2600065 | 0.72 | SMN1; SMN2 (0.46) | SMN1; SMN2CA1CA2KMT2ACA14 | |
| SCHEMBL6345758 | 0.70 | CA12 (0.40) | SMN1; SMN2CA1CA2CA14TSHR | |
| SCHEMBL30170032 | 0.70 | CA12 (0.40) | SMN1; SMN2CA1CA2CA14TSHR | |
| SCHEMBL7208166 | 0.70 | HCAR2 (0.34) | SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7485744-B2 | Iron-catalyzed allylic alkylation | Universität Dortmund (DE) | 2009-02-03 | — | — | US | disclosed |
| EP-1760055-A2 | Iron-catalysed allylic alkylation | Universität Dortmund (DE) | 2007-03-07 | — | — | EP | disclosed |
| US-4334091-A | Process for preparing halovinyl cyclopropane carboxylic acid salts | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1982-06-08 | — | — | US | disclosed |