Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207341 | 0.90 | ALDH1A1 (0.37) | HCAR2ALDH1A1HSD17B10LMNASMN1; SMN2 | |
| SCHEMBL9796908 | 0.85 | ALDH1A1 (0.37) | HCAR2ALDH1A1HSD17B10LMNASMN1; SMN2 | |
| SCHEMBL9796637 | 0.84 | MGAM (0.34) | ALDH1A1HSD17B10LMNASMN1; SMN2ALOX15 | |
| SCHEMBL9796655 | 0.81 | SMN1; SMN2 (0.30) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL10961368 | 0.80 | MAPT (0.35) | MAPT | |
| SCHEMBL10962327 | 0.80 | ALDH1A1 (0.32) | ALDH1A1LMNAMAPT | |
| SCHEMBL10910007 | 0.78 | MEN1 (0.47) | ALDH1A1HSD17B10LMNASMN1; SMN2PIN1 | |
| SCHEMBL3212385 | 0.78 | ALDH1A1 (0.40) | HCAR2ALDH1A1HSD17B10LMNAPIN1 | |
| SCHEMBL9796662 | 0.77 | MMP8 (0.36) | HCAR2ALDH1A1HSD17B10LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7344003 | 0.76 | PIN1 (0.39) | HCAR2ALDH1A1HSD17B10LMNAPIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613934-B1 | Enzymatic partial hydrolysis of a diester of malonic acid | DEGUSSA AG (DE) | 2003-09-02 | — | — | US | claimed |
| US-4599358-A | Pyrethroids | MONTEDISON, S.P.A. (IT) | 1986-07-08 | — | — | US | disclosed |
| EP-0031041-B1 | PYRETHROIDS AND THEIR PREPARATION, THEIR PESTICIDAL COMPOSITION; INTERMEDIATES AND THEIR PREPARATION | Montedison S.p.A. (IT) | 1985-02-13 | — | — | EP | disclosed |
| EP-0031041-A2 | Pyrethroids and their preparation, their pesticidal composition; intermediates and their preparation | Montedison S.p.A. (IT) | 1981-07-01 | — | — | EP | disclosed |