Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9796637 | 0.93 | MGAM (0.34) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL9796908 | 0.90 | ALDH1A1 (0.37) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL7208166 | 0.90 | HCAR2 (0.34) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL9796655 | 0.86 | SMN1; SMN2 (0.30) | ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL9796662 | 0.82 | MMP8 (0.36) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL16237398 | 0.80 | ALOX15 (0.37) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL10910007 | 0.79 | MEN1 (0.47) | ALDH1A1LMNAHSD17B10SMN1; SMN2NPSR1 | |
| SCHEMBL4337217 | 0.78 | SMN1; SMN2 (0.36) | SMN1; SMN2TSHRKMT2A | |
| SCHEMBL2048461 | 0.76 | SMN1; SMN2 (0.35) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL9796768 | 0.76 | ALDH1A1 (0.38) | ALDH1A1LMNAHSD17B10GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3164409-A1 | GROUP 8 TRANSITION METAL CATALYSTS AND METHOD FOR MAKING SAME AND PROCESS FOR USE OF SAME IN METATHESIS REACTION | Guang Ming Innovation Company (Wuhan) (CN) | 2017-05-10 | — | — | EP | disclosed |
| WO-2016000242-A1 | GROUP 8 TRANSITION METAL CATALYSTS AND METHOD FOR MAKING SAME AND PROCESS FOR USE OF SAME IN METATHESIS REACTION | GUANG MING INNOVATION COMPANY (WUHAN) (CN) | 2016-01-07 | — | — | WO | disclosed |
| US-6613934-B1 | Enzymatic partial hydrolysis of a diester of malonic acid | DEGUSSA AG (DE) | 2003-09-02 | — | — | US | disclosed |
| EP-0812819-B1 | Enantiomer-enriched tertiary hydrocarbonrest-substituted malonic acid ester and the preparation | DEGUSSA (DE) | 2001-11-28 | — | — | EP | disclosed |
| EP-0812819-A2 | Enantiomer-enriched tertiary hydrocarbonrest-substituted malonic acid ester and the preparation | HÜLS AKTIENGESELLSCHAFT (DE) | 1997-12-17 | — | — | EP | disclosed |
| EP-0163996-A1 | 2,2-Dimethyl-3-formylcyclopropanes and process for their preparation | BAYER AG (DE) | 1985-12-11 | — | — | EP | disclosed |
| EP-0059756-B1 | 7-OXOPROSTACYCLIN DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-08-28 | — | — | EP | disclosed |
| US-4489092-A | Prostanoic acid derivatives and their preparation | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-12-18 | — | — | US | disclosed |
| US-4466969-A | 7-Oxoprostacyclin derivatives and their use as hypotensives and bronchodilators | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-08-21 | — | — | US | disclosed |
| US-4359467-A | Prostanoic acid derivatives and their preparation | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-11-16 | — | — | US | disclosed |
| EP-0059756-A1 | 7-OXOPROSTACYCLIN DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF. | SCHERING AG (DE) | 1982-09-15 | — | — | EP | disclosed |
| US-4334091-A | Process for preparing halovinyl cyclopropane carboxylic acid salts | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1982-06-08 | — | — | US | disclosed |
| WO-1982001002-A1 | 7-OXOPROSTACYCLIN DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | NICKOLSON R | 1982-04-01 | — | — | WO | disclosed |
| US-4284646-A | Prostanoic acid derivatives and their preparation | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-08-18 | — | — | US | disclosed |
| US-4257975-A | 4-Halo-3,3-dimethyl-6,6,6-trihalohexanoate intermediates | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-03-24 | — | — | US | disclosed |
| US-4198347-A | 2(2,2-Dichlorovinyl)-3,3-dimethyl-cyclopropane carboxylates | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-04-15 | — | — | US | disclosed |