SCHEMBL4337560

SCHEMBL4337560

CN(c1cccc(N)c1)S(=O)(=O)CCOS(=O)(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
HSD17B1 P14061 3/20 0.33
HSD17B2 P37059 3/20 0.33
LMNA P02545 2/20 0.33
F2 P00734 2/20 0.33
PRSS1 P07477 2/20 0.33
PRSS2 P07478 2/20 0.33
PRSS3 P35030 2/20 0.33
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
CLK1 P49759 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9138138 0.84 ESR1 (0.38) ALDH1A1TSHRHSD17B10TDP1LMNA
SCHEMBL11216389 0.84 CA2 (0.39) ALDH1A1TSHRHSD17B10TDP1HSD17B1
SCHEMBL9790473 0.82 ALDH1A1 (0.37) ALDH1A1TSHRTDP1F2PRSS1
SCHEMBL9161759 0.82 CA12 (0.40) TSHRLMNAMEN1MAPTKMT2A
SCHEMBL19174852 0.79 LMNA (0.41) ALDH1A1TSHRHSD17B10TDP1HSD17B1
SCHEMBL7636290 0.78 ALDH1A1 (0.41) ALDH1A1TSHRHSD17B10TDP1LMNA
SCHEMBL11339014 0.77 ALDH1A1 (0.48) ALDH1A1TSHRHSD17B10TDP1HSD17B1
SCHEMBL1357506 0.75 ALDH1A1 (0.56) ALDH1A1TSHRHSD17B10TDP1LMNA
SCHEMBL2991209 0.72 ALDH1A1 (0.50) ALDH1A1LMNAMEN1USP2MAPT
Sulfuric Acid SCHEMBL9277102 0.72 ALDH1A1 (0.50) ALDH1A1TSHRHSD17B10TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7611628-B1 Aligned nanotubule membranes UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2009-11-03 US disclosed
US-5399674-A Dyestuffs containing pyrimidine-carboxylic acid amide radical having fiber-reactive group, processes for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1995-03-21 US disclosed
EP-0603595-A1 Fibre reactive dyes, method for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1994-06-29 EP disclosed
US-5298607-A Reactive dyes for cotton CIBA-GEIGY CORPORATION (US) 1994-03-29 US disclosed
US-4925928-A Reactive dyes containing vinylsulfonylalkylamino bound to a bis-(triazinylamino)-benzene group CIBA-GEIGY CORPORATION (US) 1990-05-15 US disclosed
US-4908436-A Reactive dyes CIBA-GEIGY CORPORATION (US) 1990-03-13 US disclosed
US-4730038-A Water-soluble disazo compounds of 1-amino-8-naphthal-3,6- or 4,6-disulfonic acid as bivalent coupling component, containing fiber-reactive groups suitable as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1988-03-08 US disclosed
US-4622390-A DYEING FIBERS OF CELLULOSE, POLYAMIDES, POLYURETHANES HOECHST AKTIENGESELLSCHAFT (DE) 1986-11-11 US disclosed