SCHEMBL4337647

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4329385	0.86	STK33 (0.44)	STK33LMNAMAPTSMN1; SMN2RAB9A
	SCHEMBL2867309	0.86	TNIK (0.44)	LMNASMN1; SMN2RAB9AKDM4ENPC1
	SCHEMBL2871502	0.85	SMN1; SMN2 (0.46)	LMNAMAPTGAASMN1; SMN2RAB9A
	SCHEMBL4338572	0.84	STK33 (0.47)	STK33APLNRLMNAMAPTGAA
	SCHEMBL4342242	0.83	HSD17B10 (0.43)	LMNAMAPTSMN1; SMN2RAB9AKDM4E
	SCHEMBL2867192	0.83	TNIK (0.41)	MAPTSMN1; SMN2MEN1KMT2AALDH1A1
	SCHEMBL4335786	0.82	MAPK10 (0.52)	KDM4EALDH1A1TNIKMAPK10
	SCHEMBL2865310	0.81	TNIK (0.40)	MAPTSMN1; SMN2ALDH1A1TNIKMAPK10
	SCHEMBL4334979	0.79	MAPT (0.44)	LMNAMAPTGAASMN1; SMN2RAB9A
	SCHEMBL4340656	0.79	MAPK10 (0.44)	SMN1; SMN2MEN1KMT2ATNIKMAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.