SCHEMBL2867192

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2865310	0.90	TNIK (0.40)	TNIKMAPK10ITKJAK2JAK3
	SCHEMBL2867309	0.87	TNIK (0.44)	TNIKMAPK10ITKJAK2JAK3
	SCHEMBL2871502	0.84	SMN1; SMN2 (0.46)	MAPK10ALDH1A1MAPTSMN1; SMN2MEN1
	SCHEMBL4337647	0.83	STK33 (0.44)	TNIKMAPK10ALDH1A1MAPTSMN1; SMN2
	SCHEMBL4335786	0.83	MAPK10 (0.52)	TNIKMAPK10ITKJAK2ALDH1A1
	SCHEMBL2867933	0.83	CDK4 (0.42)	ITKSIRT2MEN1KMT2A
	SCHEMBL13635758	0.82	MAPK10 (0.40)	TNIKMAPK10ITKJAK2JAK3
	SCHEMBL4342242	0.82	HSD17B10 (0.43)	TNIKMAPK10ITKALDH1A1MAPT
	SCHEMBL2868617	0.81	MAPK10 (0.58)	TNIKMAPK10ITKMAPKAPK2
	SCHEMBL2866702	0.80	MAPK10 (0.44)	TNIKMAPK10ITKJAK2JAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.