SCHEMBL2867309

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4335786	0.88	MAPK10 (0.52)	TNIKMAPK10ITKMAPKAPK2JAK2
	SCHEMBL2867192	0.87	TNIK (0.41)	TNIKMAPK10ITKMAPKAPK2JAK2
	SCHEMBL4337647	0.86	STK33 (0.44)	TNIKMAPK10KDM4EMEN1NPC1
	SCHEMBL2865310	0.86	TNIK (0.40)	TNIKMAPK10ITKMAPKAPK2JAK2
	SCHEMBL4342242	0.85	HSD17B10 (0.43)	TNIKMAPK10ITKKDM4EMEN1
	SCHEMBL2862889	0.84	TNIK (0.48)	TNIKMAPK10MAPKAPK2JAK2JAK3
	SCHEMBL2871502	0.84	SMN1; SMN2 (0.46)	MAPK10KDM4EMEN1NPC1ALDH1A1
	SCHEMBL4345589	0.83	MAPK10 (0.44)	TNIKMAPK10MAPKAPK2JAK2JAK3
	SCHEMBL4340656	0.83	MAPK10 (0.44)	TNIKMAPK10MAPKAPK2JAK2JAK3
	SCHEMBL2857820	0.82	ACLY (0.42)	TNIKMAPK10MAPKAPK2JAK2JAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.