SCHEMBL4337709

SCHEMBL4337709

O=C1CN(CCO)CCN1CCO

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.41
MEN1 O00255 3/20 0.40
MCHR1 Q99705 1/20 0.40
KDM4E B2RXH2 2/20 0.38
SLC6A2 P23975 2/20 0.38
SLC6A4 P31645 2/20 0.38
SLC6A3 Q01959 2/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 2/20 0.36
PIK3CD O00329 1/20 0.36
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
LMNA P02545 1/20 0.35
NPSR1 Q6W5P4 1/20 0.33
NSD2 O96028 1/20 0.33
PABPC1 P11940 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3429466 0.90 KMT2A (0.38) KMT2AMEN1MCHR1SLC6A2SLC6A4
SCHEMBL16074588 0.89 POLB (0.44) KMT2AMEN1MCHR1SLC6A2SLC6A4
SCHEMBL3429465 0.87 KMT2A (0.36) KMT2AMEN1MCHR1KDM4ESLC6A2
SCHEMBL24801766 0.86 KMT2A (0.41) KMT2AMEN1MCHR1KDM4ESLC6A2
SCHEMBL8826885 0.86 P2RX7 (0.38) KMT2AMEN1MCHR1KDM4ESLC6A2
SCHEMBL29341972 0.81 SLC6A2 (0.44) KMT2AMEN1MCHR1SLC6A2SLC6A4
SCHEMBL749892 0.79 PIK3CD (0.58) KMT2AMEN1KDM4EALDH1A1MAPT
SCHEMBL14357416 0.79 GAA (0.39) KMT2AMEN1KDM4EMAPTLMNA
SCHEMBL19049562 0.78 KMT2A (0.34) KMT2AMEN1
SCHEMBL8827083 0.77 KMT2A (0.39) KMT2AMEN1KDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014138908-A1 PROCESSES FOR THE REJUVENATION OF AN AMINE ACID GAS ABSORBENT USED IN AN ACID GAS RECOVERY UNIT CANSOLV TECHNOLOGIES INC. (CA) 2014-09-18 WO claimed
US-20140260979-A1 PROCESSES FOR THE REJUVENATION OF AN AMINE ACID GAS ABSORBENT USED IN AN ACID GAS RECOVERY UNIT CANSOLV TECHNOLOGIES INC. (CA) 2014-09-18 US claimed
US-20090305065-A1 Composition for coloring ceramic articles VIGNALI GRAZIANO 2009-12-10 US claimed
EP-2046698-A2 COMPOSITION FOR COLORING CERAMIC ARTICLES Vignali, Graziano (IT) 2009-04-15 EP claimed
WO-2008000716-A2 COMPOSITION FOR COLORING CERAMIC ARTICLES VIGNALI GRAZIANO (IT) 2008-01-03 WO claimed
EP-0552360-A1 A COMPOSITION AND METHOD FOR SIMULTANEOUS ABSORPTION OF SULFUR DIOXIDE AND NITRIC OXIDE THE DOW CHEMICAL COMPANY (US) 1993-07-28 EP claimed
WO-1993003825-A1 A COMPOSITION AND METHOD FOR SIMULTANEOUS ABSORPTION OF SULFUR DIOXIDE AND NITRIC OXIDE THE DOW CHEMICAL COMPANY (US) 1993-03-04 WO claimed
US-5167941-A Sulfur dioxide; cationic polyelectrolyte stabilizers THE DOW CHEMICAL COMPANY (US) 1992-12-01 US claimed
US-5019365-A Cationic polyelectrolyte THE DOW CHEMICAL COMPANY (US) 1991-05-28 US claimed
US-9919262-B2 Process for capturing sulfur dioxide from a gas stream SHELL OIL COMPANY (US) 2018-03-20 US disclosed
US-9919262-B2 Process for capturing sulfur dioxide from a gas stream SHELL OIL COMPANY (US) 2018-03-20 US disclosed
US-20160263519-A1 PROCESS FOR CAPTURING SULFUR DIOXIDE FROM A GAS STREAM SHELL OIL COMPANY 2016-09-15 US disclosed
US-20160263519-A1 PROCESS FOR CAPTURING SULFUR DIOXIDE FROM A GAS STREAM SHELL OIL COMPANY 2016-09-15 US disclosed
US-20140260979-A1 PROCESSES FOR THE REJUVENATION OF AN AMINE ACID GAS ABSORBENT USED IN AN ACID GAS RECOVERY UNIT CANSOLV TECHNOLOGIES INC. (CA) 2014-09-18 US disclosed
US-4980471-A Preparation of piperazinones for use as sulfur dioxide absorbents THE DOW CHEMICAL COMPANY (US) 1990-12-25 US disclosed
US-4880934-A Preparation of hydroxyalkylpiperazinones by reacting a 2,3-dihydroxy-1,4-dioxane with a hydroalkyldiamine THE DOW CHEMICAL COMPANY (US) 1989-11-14 US disclosed
US-4814443-A Preparation of hydroxyalkylpiperazinones by reacting glyoxal with hydroxyalkyldiamines THE DOW CHEMICAL COMPANY (US) 1989-03-21 US disclosed
US-4814447-A Preparation of hydroxyalkylpiperazinones by reacting an alkylene oxide with decahydropyrazino[2,3-b]pyrazine or its substituted derivatives THE DOW CHEMICAL COMPANY (US) 1989-03-21 US disclosed
EP-0303501-A2 Sulfur dioxide removal from gas streams using substituted piperazinones THE DOW CHEMICAL COMPANY (US) 1989-02-15 EP disclosed
US-4783327-A Sulfur dioxide removal from gas streams using hydroxyalkyl substituted piperazinones THE DOW CHEMICAL COMPANY (US) 1988-11-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090305065-A1 Composition for coloring ceramic articles CAD, SF3B5, FYN KMT2A 210/4885MEN1 1423/4885MCHR1 3132/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.