Isopropyl Alcohol

Isopropyl Alcohol

SCHEMBL4337774

CC(C)O.CO.ClC(Cl)Cl

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.60
LMNA P02545 2/20 0.60
TSHR P16473 4/20 0.46
TDP1 Q9NUW8 1/20 0.33
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isopropyl Alcohol SCHEMBL2167550 0.95 ALDH1A1 (0.55) ALDH1A1LMNATSHRTDP1
Isopropyl Alcohol SCHEMBL7671116 0.95 ALDH1A1 (0.67) ALDH1A1LMNATSHRTDP1TP53
Isopropyl Alcohol SCHEMBL5999087 0.95 ALDH1A1 (0.67) ALDH1A1LMNATSHRTDP1TP53
Isopropyl Alcohol SCHEMBL27497569 0.95 ALDH1A1 (0.67) ALDH1A1LMNATSHRTDP1TP53
Isopropyl Alcohol SCHEMBL52447 0.95
Isopropyl Alcohol SCHEMBL6554536 0.90
Isopropyl Alcohol SCHEMBL1150321 0.90
Isopropyl Alcohol SCHEMBL5858313 0.86 ALDH1A1 (0.55) ALDH1A1LMNATSHRTDP1
Methyl Alcohol SCHEMBL28014181 0.84
Chloroform SCHEMBL10009248 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200363419-A1 A METHOD OF DIAGNOSING CANCER BASED ON LIPIDOMIC ANALYSIS OF A BODY FLUID UNIVERZITA PARDUBICE (CZ) 2020-11-19 US disclosed
US-20200281988-A1 METHOD FOR TREATING CANCER THE UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER (US) 2020-09-10 US disclosed
US-10751376-B1 Method for treating cancer ALI JASSIM M HASSAN M (KW) 2020-08-25 US disclosed
US-10568915-B1 Method of preparing a therapeutic composition using a preparation from epidermal gel secretions of catfish ALI JASSIM M HASSAN M (KW) 2020-02-25 US disclosed
US-10471105-B1 Method for treating infertility ALI JASSIM M HASSAN M (KW) 2019-11-12 US disclosed
US-10406205-B1 Method for curing diabetes and damaged organs and tissues affected by diabetes ALI JASSIM M HASSAN M (KW) 2019-09-10 US disclosed
US-20180267066-A1 LIPODOMIC BIOMARKERS OF METABOLIC DISEASES IN DAIRY COWS BRIGHAM YOUNG UNIVERSITY (US) 2018-09-20 US disclosed
WO-2013173642-A1 HIGH-THROUGHPUT LIPIDOMICS SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) 2013-11-21 WO disclosed
US-20130225694-A1 COMPOSITIONS AND METHODS OF INHIBITING RETINAL DEGENERATION OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) 2013-08-29 US disclosed
EP-2116524-B1 The sodium salt of retinoyl-cysteic acid and retinoyl-cysteine sulfinic acid ARDENIA INVESTMENTS LTD (GB) 2012-10-03 EP disclosed
EP-1826198-A1 Method for the synthesis of the sodium salt of retinoyl-cysteic acid and retinoyl-cysteine sulfinic acid Ardenia Investments Ltd. (GB) 2007-08-29 EP disclosed
EP-1387844-B1 RETINOL DERIVATIVES POTENTIATION OF ACTIVE SUBSTANCES BY MICELLAR PREPARATION ARDENIA INVESTMENTS LTD (GB) 2007-06-13 EP disclosed
EP-1387844-A1 RETINOL DERIVATIVES POTENTIATION OF ACTIVE SUBSTANCES BY MICELLAR PREPARATION Ardenia Investments Ltd. (GB) 2004-02-11 EP disclosed
US-6642271-B2 Capable of potentiating the efficacy of therapeutically active compounds, for example cytotoxic compounds used in the treatment of cancer ARDENIA INVESTMENTS, LTD. (GB) 2003-11-04 US disclosed
US-20030050343-A1 Novel potentiating compounds OASMIA PHARMACEUTICAL AB (SE) 2003-03-13 US disclosed
WO-2002092600-A1 RETINOL DERIVATIVES POTENTIATION OF ACTIVE SUBSTANCES BY MICELLAR PREPARATION ARDENIA INVESTMENTS LTD. (GB) 2002-11-21 WO disclosed
US-4895853-A Antitumor alkaloids HARBOR BRANCH OCEANOGRAPHIC INSTITUTION, INC. (US) 1990-01-23 US disclosed
EP-0272056-A1 New antitumor alkaloids HARBOR BRANCH OCEANOGRAPHIC INSTITUTION, INC. (US) 1988-06-22 EP disclosed
US-4529561-A Pressurized extrusion through a porous membrane THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1985-07-16 US disclosed
EP-0036676-B1 METHOD OF MAKING UNIFORMLY SIZED LIPOSOMES AND LIPOSOMES SO MADE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1984-07-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130225694-A1 COMPOSITIONS AND METHODS OF INHIBITING RETINAL DEGENERATION ALDH1A2, PDE6C, NQO1 ALDH1A1 283/4885LMNA 780/4885TSHR 4475/4885
US-20030050343-A1 Novel potentiating compounds MCL1, BAD, PMAIP1 ALDH1A1 4014/4885LMNA 3296/4885TSHR 4111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.