Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL8196434 | 0.91 | SLC6A2 (0.34) | SLC6A2SLC6A4IRAK4SLC6A3TP53 | |
| Lactic Acid SCHEMBL8031251 | 0.86 | SLC6A2 (0.37) | SLC6A2SLC6A4IRAK4SLC6A3TP53 | |
| Lactic Acid SCHEMBL28188149 | 0.85 | EPHX1 (0.33) | SLC6A2SLC6A4IRAK4SLC6A3ADRB2 | |
| Lactic Acid SCHEMBL4170980 | 0.84 | SLC6A2 (0.38) | SLC6A2SLC6A4IRAK4SLC6A3TP53 | |
| SCHEMBL23710060 | 0.83 | — | — | |
| SCHEMBL185653 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL6025691 | 0.82 | SLC6A4 (0.39) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| Hydrazine SCHEMBL8554314 | 0.82 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| Lactic Acid SCHEMBL27651674 | 0.80 | GPR84 (0.35) | — | |
| Octadecanoic Acid Amide SCHEMBL28187430 | 0.78 | SOAT1 (0.35) | IRAK4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024478-A1 | AQUEOUS LAUNDRY DETERGENT COMPOSITIONS HAVING IMPROVED SOFTENING AND ANTISTATIC PROPERTIES | Akzo Nobel N.V. (NL) | 2009-02-18 | — | — | EP | claimed |
| WO-2008000333-A1 | AQUEOUS LAUNDRY DETERGENT COMPOSITIONS HAVING IMPROVED SOFTENING AND ANTISTATIC PROPERTIES | AKZO NOBEL N.V. (NL) | 2008-01-03 | — | — | WO | claimed |