Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL4337807 | 0.91 | SLC6A2 (0.35) | SLC6A2SLC6A4IRAK4SLC6A3ADRB2 | |
| Lactic Acid SCHEMBL28188149 | 0.88 | EPHX1 (0.33) | SLC6A2SLC6A4IRAK4BRD4SLC6A3 | |
| Lactic Acid SCHEMBL27651674 | 0.88 | GPR84 (0.35) | — | |
| SCHEMBL72780 | 0.84 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| SCHEMBL20929877 | 0.84 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| Lactic Acid SCHEMBL8031251 | 0.84 | SLC6A2 (0.37) | SLC6A2SLC6A4IRAK4BRD4SLC6A3 | |
| Hydrazine SCHEMBL8557573 | 0.83 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| Lactic Acid SCHEMBL4170980 | 0.82 | SLC6A2 (0.38) | SLC6A2SLC6A4IRAK4SLC6A3ADRB2 | |
| SCHEMBL8557599 | 0.80 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| Morpholine SCHEMBL8341254 | 0.79 | MEN1 (0.37) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220097-A1 | ORGANIC RICINOLEATE SALTS AS DEODORIZING AGENTS | COLONIAL CHEMICAL, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| EP-3500601-B1 | ENCAPSULATED MATERIALS WITH IMPROVED PROPERTIES | SUN CHEMICAL CORP (US) | 2021-07-28 | — | — | EP | disclosed |
| US-20210214561-A1 | ENCAPSULATED MATERIALS WITH IMPROVED PROPERTIES | SUN CHEMICAL CORPORATION (US) | 2021-07-15 | — | — | US | disclosed |
| EP-3500601-A1 | ENCAPSULATED MATERIALS WITH IMPROVED PROPERTIES | Sun Chemical Corporation (US) | 2019-06-26 | — | — | EP | disclosed |
| WO-2018035325-A1 | ENCAPSULATED MATERIALS WITH IMPROVED PROPERTIES | SUN CHEMICAL CORPORATION (US) | 2018-02-22 | — | — | WO | disclosed |
| CN-1678282-A | Compositions of anionic polymeric rheology modifiers and cationic materials | NOVEON IP HOLDINGS CORP (US) | 2005-10-05 | — | — | CN | disclosed |
| CN-1157426-C | Branched/block copolymer for treatment of keratinous substrates | ŵ�ֶ�IP�عɹ�˾ | 2004-07-14 | — | — | CN | disclosed |
| US-6165454-A | Stabilized hair care products | COLGATE-PALMOLIVE COMPANY (US) | 2000-12-26 | — | — | US | disclosed |
| EP-1014917-A1 | STABILIZED HAIR CARE PRODUCTS | Colgate-Palmolive Company (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999013837-A1 | STABILIZED HAIR CARE PRODUCTS | COLGATE-PALMOLIVE COMPANY (US) | 1999-03-25 | — | — | WO | disclosed |
| EP-0410659-A2 | Method and composition to impart improved conditioning properties to the hair | HELENE CURTIS, INC. (US) | 1991-01-30 | — | — | EP | disclosed |