Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ACP3 | P15309 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30632615 | 1.00 | HTT (0.60) | HTTALDH1A1POLBMEN1KMT2A | |
| Nitrogen SCHEMBL29173898 | 0.97 | HTT (0.57) | HTTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL12992995 | 0.85 | SLC7A5 (0.52) | HTTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL34460099 | 0.85 | SLC7A5 (0.52) | HTTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL11233308 | 0.85 | FFAR1 (0.65) | HTTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL7640356 | 0.84 | MEN1 (0.56) | HTTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL365306 | 0.84 | FFAR4 (0.54) | HTTALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL30645136 | 0.84 | FFAR4 (0.54) | HTTALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL701131 | 0.84 | ALDH1A1 (0.61) | HTTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL5692025 | 0.84 | BACE1 (0.60) | MEN1KMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117164593-A | Pyrimidoindoles compound, preparation method and application thereof, and anti-erythroleukemia drug | 贵州省天然产物研究中心 | 2023-12-05 | — | — | CN | claimed |
| WO-2025235367-A1 | AZAINDOLINONE COMPOUNDS AS KCA3.1 POTASSIUM CHANNEL BLOCKERS | D. E. SHAW RESEARCH, LLC (US) | 2025-11-13 | — | — | WO | disclosed |
| US-20250282749-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2025-09-11 | — | — | US | disclosed |
| EP-4469445-A1 | COMPOUNDS AND METHODS OF USE | Tango Therapeutics, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| CN-118702710-A | Method for synthesizing organoboron compound by visible light catalysis | 常州大学 | 2024-09-27 | — | — | CN | disclosed |
| CN-113968854-B | Novel onium salt compound and synthesis and application thereof | 东莞市东阳光农药研发有限公司 | 2024-08-09 | — | — | CN | disclosed |
| CN-117736104-A | Method for synthesizing butanedicarboxylate derivative by visible light catalysis | 常州大学 | 2024-03-22 | — | — | CN | disclosed |
| CN-117164593-A | Pyrimidoindoles compound, preparation method and application thereof, and anti-erythroleukemia drug | 贵州省天然产物研究中心 | 2023-12-05 | — | — | CN | disclosed |
| CN-115417738-B | Photo-induced alpha-hydrofluorination method for diazoaryl ester compound | 哈尔滨工业大学（深圳） | 2023-10-03 | — | — | CN | disclosed |
| CN-112851665-B | Novel mesoionic compounds and their use in agriculture | 东莞市东阳光农药研发有限公司 | 2023-08-08 | — | — | CN | disclosed |
| US-4735940-A | Tricyclic pyridine derivatives and pharmaceutical compositions | HOFFMANN-LA ROCHE INC. (US) | 1988-04-05 | — | — | US | disclosed |
| CN-85108120-A | The preparation of tricyclic pyridine derivative and application thereof | — | 1986-11-05 | — | — | CN | disclosed |
| US-4544752-A | TREATMENT OF GOUT; ANTIARTHRITIC AGENTS | ELI LILLY AND COMPANY (US) | 1985-10-01 | — | — | US | disclosed |
| EP-0048615-B1 | IMPROVEMENTS IN OR RELATING TO 3-ARYL-5-ISOTHIAZOLE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1984-05-30 | — | — | EP | disclosed |
| US-4426536-A | Synthesis of phenylacetic acid esters | ELI LILLY AND COMPANY (US) | 1984-01-17 | — | — | US | disclosed |
| US-4346094-A | ENZYME INHIBITORS | ELI LILLY AND COMPANY (US) | 1982-08-24 | — | — | US | disclosed |
| EP-0048615-A1 | Improvements in or relating to 3-aryl-5-isothiazole derivatives | ELI LILLY AND COMPANY (US) | 1982-03-31 | — | — | EP | disclosed |
| US-4260620-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1981-04-07 | — | — | US | disclosed |
| US-4202901-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1980-05-13 | — | — | US | disclosed |
| US-4197302-A | HYPOTENSIVE AGENTS, 5-ETHERIFIED, ALSO ESTERS, AMIDES, HYDRAZIDES | CIBA-GEIGY CORPORATION (US) | 1980-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250282749-A1 | COMPOUNDS AND METHODS OF USE | CYP1B1, CYP2C19, UGT1A1 | HTT 1768/4885ALDH1A1 193/4885POLB 929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.