Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.65 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11236732 | 0.89 | FFAR1 (0.61) | FFAR1FFAR4HTTALDH1A1POLB | |
| SCHEMBL11244569 | 0.88 | FFAR1 (0.76) | FFAR1FFAR4POLBRXFP1THRB | |
| SCHEMBL11240957 | 0.87 | FFAR1 (0.67) | FFAR1FFAR4HTTALDH1A1RXFP1 | |
| SCHEMBL30632615 | 0.85 | HTT (0.60) | HTTALDH1A1POLBTDP1SMN1; SMN2 | |
| SCHEMBL4338 | 0.85 | HTT (0.60) | HTTALDH1A1POLBTDP1SMN1; SMN2 | |
| Nitrogen SCHEMBL29173898 | 0.83 | HTT (0.57) | HTTALDH1A1POLBTDP1SMN1; SMN2 | |
| SCHEMBL11249779 | 0.80 | FFAR1 (0.71) | FFAR1FFAR4HTTALDH1A1THRB | |
| SCHEMBL11242235 | 0.80 | FFAR1 (0.80) | FFAR1FFAR4RXFP1TDP1HDAC1 | |
| SCHEMBL11235397 | 0.79 | FFAR1 (0.70) | FFAR1FFAR4HTTPOLBRXFP1 | |
| SCHEMBL5692025 | 0.79 | BACE1 (0.60) | MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362892-A | ARALKYLANILINES, ANTICHOLESTEROL AGENTS | BEECHAM GROUP LIMITED (GB) | 1982-12-07 | — | — | US | disclosed |
| US-4206145-A | ALKANOYL-SUBSTITUTED ARALKYLAMINES | BEECHAM GROUP LIMITED (GB) | 1980-06-03 | — | — | US | disclosed |