Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL4341470 | 0.81 | DNM1 (0.36) | DNM1TSHRLMNAALDH1A1ALDH2 | |
| Iodide SCHEMBL4344104 | 0.79 | DNM1 (0.35) | DNM1ALDH1A1ALDH2CA12CA1 | |
| Iodide SCHEMBL4342956 | 0.79 | DNM1 (0.35) | DNM1CA12CA1CA9 | |
| Bromide SCHEMBL7669293 | 0.76 | DNM1 (0.36) | DNM1TSHRLMNAALDH1A1ALDH2 | |
| Hydrochloric Acid SCHEMBL3606950 | 0.76 | DNM1 (0.36) | DNM1TSHRLMNAALDH1A1ALDH2 | |
| Bromide SCHEMBL3605614 | 0.74 | DNM1 (0.35) | DNM1ALDH1A1ALDH2CA12CA1 | |
| Iodide SCHEMBL4343388 | 0.72 | DNM1 (0.37) | DNM1ALDH1A1ALDH2CA12CA1 | |
| Iodide SCHEMBL6151762 | 0.71 | CA12 (0.39) | DNM1TSHRLMNAALDH1A1ALDH2 | |
| Hydrochloric Acid SCHEMBL3593887 | 0.67 | DNM1 (0.50) | DNM1TSHRCA12CA1CA9 | |
| Hydrochloric Acid SCHEMBL1357309 | 0.67 | DNM1 (0.50) | DNM1TSHRCA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1956026-B1 | IONIC LIQUID CONTAINING PHOSPHONIUM CATION HAVING P-N BOND AND METHOD FOR PRODUCING SAME | KANTO DENKA KOGYO KK (JP) | 2016-11-30 | — | — | EP | disclosed |
| US-8871974-B2 | Ionic liquid containing phosphonium cation having P—N bond and method for producing same | KANTO DENKA KOGYO CO., LTD. (JP) | 2014-10-28 | — | — | US | disclosed |
| US-20090163394-A1 | IONIC LIQUID CONTAINING PHOSPHONIUM CATION HAVING P-N BOND AND METHOD FOR PRODUCING SAME | KANTO DENKA KOGYO CO., LTD. (JP) | 2009-06-25 | — | — | US | disclosed |
| EP-1956026-A1 | IONIC LIQUID CONTAINING PHOSPHONIUM CATION HAVING P-N BOND AND METHOD FOR PRODUCING SAME | Kanto Denka Kogyo CO., LTD. (JP) | 2008-08-13 | — | — | EP | disclosed |