Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.30 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL4341470 | 0.87 | DNM1 (0.36) | DNM1CA12CA1CA9CA2 | |
| Iodide SCHEMBL4344104 | 0.85 | DNM1 (0.35) | DNM1CA12CA1CA9CA2 | |
| Iodide SCHEMBL4343388 | 0.83 | DNM1 (0.37) | DNM1CA12CA1CA9CA2 | |
| Iodide SCHEMBL6151091 | 0.82 | CA12 (0.37) | DNM1CA12CA1CA9CA2 | |
| Iodide SCHEMBL4346703 | 0.82 | CA12 (0.37) | DNM1CA12CA1CA9CA2 | |
| Iodide SCHEMBL4338243 | 0.79 | DNM1 (0.38) | DNM1CA12CA1CA9 | |
| Iodide SCHEMBL4336908 | 0.78 | — | — | |
| Bromide SCHEMBL7929786 | 0.77 | CA12 (0.32) | DNM1CA12CA1CA9CA2 | |
| Bromide SCHEMBL6731553 | 0.77 | CA12 (0.37) | DNM1CA12CA1CA9CA2 | |
| Iodide SCHEMBL4337720 | 0.76 | DNM1 (0.46) | DNM1CA12CA1CA9CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1956026-B1 | IONIC LIQUID CONTAINING PHOSPHONIUM CATION HAVING P-N BOND AND METHOD FOR PRODUCING SAME | KANTO DENKA KOGYO KK (JP) | 2016-11-30 | — | — | EP | disclosed |
| US-8871974-B2 | Ionic liquid containing phosphonium cation having P—N bond and method for producing same | KANTO DENKA KOGYO CO., LTD. (JP) | 2014-10-28 | — | — | US | disclosed |
| US-20090163394-A1 | IONIC LIQUID CONTAINING PHOSPHONIUM CATION HAVING P-N BOND AND METHOD FOR PRODUCING SAME | KANTO DENKA KOGYO CO., LTD. (JP) | 2009-06-25 | — | — | US | disclosed |
| EP-1956026-A1 | IONIC LIQUID CONTAINING PHOSPHONIUM CATION HAVING P-N BOND AND METHOD FOR PRODUCING SAME | Kanto Denka Kogyo CO., LTD. (JP) | 2008-08-13 | — | — | EP | disclosed |