Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL4341470 | 0.92 | DNM1 (0.36) | DNM1CA12CA1CA9ALDH1A1 | |
| Iodide SCHEMBL4342956 | 0.85 | DNM1 (0.35) | DNM1CA12CA1CA9CA2 | |
| Iodide SCHEMBL4343388 | 0.83 | DNM1 (0.37) | DNM1CA12CA1CA9ALDH1A1 | |
| Iodide SCHEMBL4336575 | 0.82 | — | — | |
| Iodide SCHEMBL4338243 | 0.79 | DNM1 (0.38) | DNM1CA12CA1CA9ALDH1A1 | |
| Iodide SCHEMBL6151762 | 0.78 | CA12 (0.39) | DNM1CA12CA1CA9ALDH1A1 | |
| Iodide SCHEMBL6151012 | 0.78 | CA1 (0.32) | CA12CA1CA9CA2 | |
| Iodide SCHEMBL4337720 | 0.76 | DNM1 (0.46) | DNM1CA12CA1CA9CA2 | |
| Iodide SCHEMBL6151014 | 0.75 | DNM1 (0.46) | DNM1CA12CA1CA9CA2 | |
| Iodide SCHEMBL6151558 | 0.75 | DNM1 (0.46) | DNM1CA12CA1CA9CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1956026-B1 | IONIC LIQUID CONTAINING PHOSPHONIUM CATION HAVING P-N BOND AND METHOD FOR PRODUCING SAME | KANTO DENKA KOGYO KK (JP) | 2016-11-30 | — | — | EP | disclosed |
| US-8871974-B2 | Ionic liquid containing phosphonium cation having P—N bond and method for producing same | KANTO DENKA KOGYO CO., LTD. (JP) | 2014-10-28 | — | — | US | disclosed |
| US-20090163394-A1 | IONIC LIQUID CONTAINING PHOSPHONIUM CATION HAVING P-N BOND AND METHOD FOR PRODUCING SAME | KANTO DENKA KOGYO CO., LTD. (JP) | 2009-06-25 | — | — | US | disclosed |
| EP-1956026-A1 | IONIC LIQUID CONTAINING PHOSPHONIUM CATION HAVING P-N BOND AND METHOD FOR PRODUCING SAME | Kanto Denka Kogyo CO., LTD. (JP) | 2008-08-13 | — | — | EP | disclosed |