Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11539890 | 0.79 | NOTUM (0.47) | NOTUMMAPTNPC1L3MBTL1ALDH1A1 | |
| SCHEMBL11539893 | 0.79 | NOTUM (0.47) | NOTUMMAPTNPC1L3MBTL1ALDH1A1 | |
| SCHEMBL12609459 | 0.78 | NOTUM (0.43) | NOTUMMAPTRAB9ACYP3A4NPC1 | |
| SCHEMBL17146135 | 0.75 | MEN1 (0.40) | NOTUMMAPTL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL10556400 | 0.75 | MAPK8 (0.52) | MAPK8MAPK9MAPK10MAPTPOLB | |
| SCHEMBL13167842 | 0.75 | MEN1 (0.40) | NOTUMMAPTL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL11540587 | 0.75 | NOTUM (0.40) | NOTUMMAPTRAB9ACYP3A4NPC1 | |
| SCHEMBL11539391 | 0.75 | NOTUM (0.40) | NOTUMMAPTRAB9ACYP3A4NPC1 | |
| SCHEMBL11540152 | 0.75 | LMNA (0.41) | NOTUMMAPTRAB9ACYP3A4NPC1 | |
| SCHEMBL11540155 | 0.75 | LMNA (0.41) | NOTUMMAPTRAB9ACYP3A4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4108873-A | O-(carboxymethyl)-4-chromanone oxime | MORTON-NORWICH PRODUCTS, INC. (US) | 1978-08-22 | — | — | US | claimed |
| US-9642854-B2 | Flavanoid compounds and process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-05-09 | — | — | US | disclosed |
| US-20150174135-A1 | FLAVANOID COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2015-06-25 | — | — | US | disclosed |
| US-20120022062-A1 | Flavanoid Compounds and Process for Preparation Thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-01-26 | — | — | US | disclosed |
| US-4108873-A | O-(carboxymethyl)-4-chromanone oxime | MORTON-NORWICH PRODUCTS, INC. (US) | 1978-08-22 | — | — | US | disclosed |
| US-4108873-A | O-(carboxymethyl)-4-chromanone oxime | MORTON-NORWICH PRODUCTS, INC. (US) | 1978-08-22 | — | — | US | disclosed |
| US-4108873-A | O-(carboxymethyl)-4-chromanone oxime | MORTON-NORWICH PRODUCTS, INC. (US) | 1978-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150174135-A1 | FLAVANOID COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | F2, FOXM1, HRH2 | MAPK8 2690/4885MAPK9 2519/4885MAPK10 2133/4885 |
| US-20120022062-A1 | Flavanoid Compounds and Process for Preparation Thereof | F2, FOXM1, HRH2 | MAPK8 2690/4885MAPK9 2519/4885MAPK10 2133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.