Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 10/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.40 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13578189 | 0.94 | MAP2K3 (0.45) | RORCPPARGMAP2K3HTR4GRM7 | |
| Trifluoroacetic Acid SCHEMBL4339626 | 0.90 | MAP2K3 (0.53) | RORCPPARGMAP2K3HTR4KDM4E | |
| Trifluoroacetic Acid SCHEMBL4339713 | 0.87 | CSNK1D (0.46) | RORCPPARGHTR4CNR1CSNK1D | |
| Trifluoroacetic Acid SCHEMBL4339706 | 0.86 | RORC (0.42) | RORCPPARGMAP2K3HTR4CNR1 | |
| Trifluoroacetic Acid SCHEMBL4325276 | 0.86 | GUCY1B2 (0.43) | RORCPPARGMAP2K3KDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL4318631 | 0.85 | ATM (0.45) | RORCPPARGHTR4 | |
| Trifluoroacetic Acid SCHEMBL4326422 | 0.84 | L3MBTL1 (0.42) | RORCPPARGMAP2K3HTR4KDM4E | |
| Trifluoroacetic Acid SCHEMBL4325196 | 0.83 | RORC (0.43) | RORCPPARGMAP2K3 | |
| SCHEMBL13578146 | 0.83 | MAP2K3 (0.60) | RORCMAP2K3HTR4KDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL4331249 | 0.82 | GABRA5 (0.40) | RORCPPARGHTR4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325936-A1 | IMIDAZOPYRIDINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | MERCK & CO., INC. | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325936-A1 | IMIDAZOPYRIDINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | CNR2, CNR1, TRPV1 | RORC 135/4885PPARG 103/4885MAP2K3 1970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.