Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22285592 | 1.00 | ALDH1A1 (0.56) | ALDH1A1EPHX1MEN1KMT2AGAA | |
| SCHEMBL22285596 | 1.00 | ALDH1A1 (0.56) | ALDH1A1EPHX1MEN1KMT2AGAA | |
| SCHEMBL433979 | 1.00 | ALDH1A1 (0.56) | ALDH1A1EPHX1MEN1KMT2AGAA | |
| SCHEMBL2326093 | 1.00 | ALDH1A1 (0.56) | ALDH1A1EPHX1MEN1KMT2AGAA | |
| SCHEMBL9398324 | 1.00 | ALDH1A1 (0.56) | ALDH1A1EPHX1MEN1KMT2AGAA | |
| SCHEMBL25447123 | 1.00 | ALDH1A1 (0.56) | ALDH1A1EPHX1MEN1KMT2AGAA | |
| SCHEMBL7333566 | 0.99 | ALDH1A1 (0.54) | ALDH1A1EPHX1MEN1KMT2AGAA | |
| SCHEMBL7810127 | 0.99 | ALDH1A1 (0.54) | ALDH1A1EPHX1MEN1KMT2AGAA | |
| SCHEMBL7337637 | 0.96 | ALDH1A1 (0.52) | ALDH1A1EPHX1MEN1KMT2AGAA | |
| SCHEMBL2163641 | 0.93 | CTRB1 (0.52) | ALDH1A1MEN1KMT2AGAACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477639-B1 | Substituted amino acid amide derivatives, their preparation and use | BAYER AG (DE) | 1995-04-12 | — | — | EP | claimed |
| EP-3303367-B1 | STABILIZED MINIMAL COILED-COIL MIMETICS | UNIV NEW YORK (US) | 2025-06-18 | — | — | EP | disclosed |
| EP-4425181-A1 | COMPOSITION FOR DETECTING OR MEASURING ANALYTE | Bertis Inc (KR) | 2024-09-04 | — | — | EP | disclosed |
| US-20240124539-A1 | CROSSLINKED HELIX DIMER MIMICS OF SOS AND METHODS OF USING SAME | NEW YORK UNIVERSITY | 2024-04-18 | — | — | US | disclosed |
| US-20240011979-A1 | COMPOSITION FOR DETECTING OR MEASURING ANALYTES | BERTIS INC. (KR) | 2024-01-11 | — | — | US | disclosed |
| CN-116829949-A | Compositions for detecting or measuring analytes | 伯蒂斯有限公司 | 2023-09-29 | — | — | CN | disclosed |
| WO-2023075435-A1 | COMPOSITION FOR DETECTING OR MEASURING ANALYTE | 주식회사 베르티스 | 2023-05-04 | — | — | WO | disclosed |
| US-20220283131-A1 | COMPOSITION FOR DETECTING OR MEASURING ANALYTES | BERTIS CO., LTD. (KR) | 2022-09-08 | — | — | US | disclosed |
| WO-2022050529-A1 | COMPOSITION FOR DETECTING OR MEASURING ANALYTE | ㈜베르티스 | 2022-03-10 | — | — | WO | disclosed |
| US-9498483-B2 | 2,3,5-trisubstituted thiophene compounds and uses thereof | NOVARTIS AG (CH) | 2016-11-22 | — | — | US | disclosed |
| US-9040690-B2 | 2,3,5-trisubstituted thiophene compounds and uses thereof | NOVARTIS AG (CH) | 2015-05-26 | — | — | US | disclosed |
| EP-2595983-A1 | 2,3,5-TRISUBSTITUTED THIOPHENE COMPOUNDS AND USES THEREOF | Novartis AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| US-20130123252-A1 | 2,3,5-Trisubstituted Thiophene Compounds and Uses Thereof | NOVARTIS AG (CH) | 2013-05-16 | — | — | US | disclosed |
| US-20130123252-A1 | 2,3,5-Trisubstituted Thiophene Compounds and Uses Thereof | NOVARTIS AG (CH) | 2013-05-16 | — | — | US | disclosed |
| US-20130123252-A1 | 2,3,5-Trisubstituted Thiophene Compounds and Uses Thereof | NOVARTIS AG (CH) | 2013-05-16 | — | — | US | disclosed |
| WO-2012010663-A9 | 2,3,5-TRISUBSTITUTED THIOPHENE COMPOUNDS AND USES THEREOF | NOVARTIS AG (CH) | 2013-01-24 | — | — | WO | disclosed |
| WO-2012010663-A9 | 2,3,5-TRISUBSTITUTED THIOPHENE COMPOUNDS AND USES THEREOF | NOVARTIS AG (CH) | 2013-01-24 | — | — | WO | disclosed |
| CN-102485743-A | Antineoplastic compound | BEIJING HANMEI PHARMACEUTICAL CO LTD | 2012-06-06 | — | — | CN | disclosed |
| WO-2012010663-A1 | 2,3,5-TRISUBSTITUTED THIOPHENE COMPOUNDS AND USES THEREOF | NOVARTIS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012010663-A1 | 2,3,5-TRISUBSTITUTED THIOPHENE COMPOUNDS AND USES THEREOF | NOVARTIS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123252-A1 | 2,3,5-Trisubstituted Thiophene Compounds and Uses Thereof | TPMT, CYP3A5, CYP11B2 | ALDH1A1 283/4885EPHX1 1440/4885MEN1 2306/4885 |
| US-20240124539-A1 | CROSSLINKED HELIX DIMER MIMICS OF SOS AND METHODS OF USING SAME | SOS2, SOS1, F2 | ALDH1A1 3199/4885EPHX1 699/4885MEN1 452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.