SCHEMBL4059702

SCHEMBL4059702

C=C(C)C(=O)O[SiH](CCC)O[Si](OC)(OC)OC

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
TSHR P16473 3/20 0.34
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3998703 0.84 TSHR (0.33) TSHRTHRB
SCHEMBL4340349 0.83 TSHR (0.36) ALDH1A1TSHRTHRB
SCHEMBL524128 0.81 ALDH1A1 (0.41) ALDH1A1TSHRTHRB
SCHEMBL9240926 0.81 TSHR (0.34) ALDH1A1TSHRTHRB
SCHEMBL3446474 0.76 THRB (0.39) ALDH1A1TSHRTHRB
SCHEMBL10703811 0.76 TSHR (0.42) ALDH1A1TSHRTHRB
SCHEMBL919874 0.73 TSHR (0.39) ALDH1A1TSHRTHRB
SCHEMBL919921 0.73 TSHR (0.36) ALDH1A1TSHRTHRB
SCHEMBL10766755 0.73 TSHR (0.41) ALDH1A1TSHRTHRB
SCHEMBL4937924 0.72 ALDH1A1 (0.33) ALDH1A1TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1621560-B1 Hyperbranched polymer comprising selected monomers, composition and cosmetic process OREAL (FR) 2008-06-04 EP claimed
US-7541414-B2 Hyperbranched copolymer comprising monomers of choice, a composition, and a cosmetic method L'OREAL S.A. (FR) 2009-06-02 US disclosed
US-20080267893-A1 HYPERBRANCHED COPOLYMER COMPRISING MONOMERS OF CHOICE, A COMPOSITION, AND A COSMETIC METHOD L'OREAL S.A. 2008-10-30 US disclosed
US-7423104-B2 Hyperbranched copolymer comprising monomers of choice, a composition, and a cosmetic method L'OREAL, S.A. (FR) 2008-09-09 US disclosed
US-20060030686-A1 Hyperbranched copolymer comprising monomers of choice, a composition, and a cosmetic method L'OREAL S.A. (FR) 2006-02-09 US disclosed
US-5629388-A POLYMERIZING MIXTURE OF POLYDIORGANOSILOXANE, CROSSLINKER AND GRAFTING AGENT AND THEN WITH VINYL FUNCTIONAL MONOMER GENERAL ELECTRIC COMPANY (US) 1997-05-13 US disclosed
EP-0557038-A1 Process for producing polydiorganosiloxane based graft copolymers GENERAL ELECTRIC COMPANY (US) 1993-08-25 EP disclosed
US-4414375-A Oxygen permeable contact lens material comprising copolymers of multifunctional siloxanyl alkylesters DOME PATENT L.P., A CA PARTNERSHIP 1983-11-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080267893-A1 HYPERBRANCHED COPOLYMER COMPRISING MONOMERS OF CHOICE, A COMPOSITION, AND A COSMETIC METHOD KRT18, MMAB, FGB ALDH1A1 307/4885TSHR 4625/4885THRB 1904/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.