Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6446557 | 0.90 | — | — | |
| SCHEMBL1778645 | 0.78 | KMO (0.40) | KMT2AKDM4EMAPTL3MBTL1 | |
| SCHEMBL2190332 | 0.77 | HSP90AB1 (0.36) | MAPT | |
| SCHEMBL1777247 | 0.77 | NPC1 (0.38) | PTGDR2KMT2AKDM4EMAPTNPC1 | |
| SCHEMBL7838303 | 0.77 | PTGDR2 (0.35) | PTGDR2MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL10631828 | 0.77 | CEL (0.36) | PTGDRPTGDR2MEN1KMT2ANPC1 | |
| SCHEMBL433060 | 0.77 | PTGDR2 (0.35) | PTGDR2MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL434766 | 0.77 | CEL (0.36) | PTGDRPTGDR2MEN1KMT2ANPC1 | |
| SCHEMBL28299092 | 0.76 | HDAC8 (0.38) | KMT2AMAPT | |
| SCHEMBL9730874 | 0.74 | PTGDR2 (0.33) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595985-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| EP-2595984-A1 | MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012010568-A1 | MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012010567-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |