Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1778645 | 0.98 | KMO (0.40) | HDAC8HDAC4HDAC2ACMSDKMO | |
| SCHEMBL2097686 | 0.82 | QDPR (0.49) | MAPT | |
| SCHEMBL3147251 | 0.78 | HSP90AA1 (0.43) | HDAC8ACMSDBACE1EPHX2HSP90AA1 | |
| SCHEMBL1116702 | 0.78 | CEL (0.34) | CYP2D6SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL9330891 | 0.78 | NPC1 (0.36) | MAPT | |
| SCHEMBL11270086 | 0.78 | HDAC4 (0.37) | HDAC8HDAC4HDAC2ACMSDKMO | |
| SCHEMBL9730874 | 0.78 | PTGDR2 (0.33) | — | |
| SCHEMBL1636811 | 0.78 | HDAC8 (0.37) | HDAC8HDAC4HDAC2ACMSDKMO | |
| SCHEMBL7754074 | 0.77 | HDAC4 (0.34) | HDAC8HDAC4HDAC2ACMSDKMO | |
| SCHEMBL432693 | 0.76 | KMO (0.39) | HDAC8HDAC4HDAC2ACMSDKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110372756-A | Bivalent platinum complex and preparation method and application thereof | 南京工业大学 | 2019-10-25 | — | — | CN | claimed |
| CN-109748938-A | Bivalent platinum complex, application thereof and organic photoelectric device | 南京工业大学 | 2019-05-14 | — | — | CN | claimed |