SCHEMBL4340748

SCHEMBL4340748

CC1(C)c2ccc(C(=O)O)cc2C(C)(c2ccc(C(=O)O)cc2)C1c1cc(C(=O)O)cc(C(=O)O)c1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RXRA P19793 15/20 0.40
RARB P10826 8/20 0.40
RXRB P28702 7/20 0.40
RARG P13631 7/20 0.40
RXRG P48443 4/20 0.40
RARA P10276 7/20 0.39
CYP26A1 O43174 5/20 0.39
CYP3A4 P08684 2/20 0.39
CYP26B1 Q9NR63 3/20 0.38
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
CYP2C19 P33261 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5958163 0.82 KMO (0.40) RXRARARBRARGRARACYP26A1
SCHEMBL10872318 0.79 RXRA (0.43) RXRARARBRXRBRARGRXRG
SCHEMBL9653876 0.71 RXRA (0.42) RXRARARBRXRBRARGRXRG
SCHEMBL11524232 0.69 GAA (0.42) RXRARARBRXRBRARGRXRG
SCHEMBL7473932 0.69 GAA (0.42) RXRARARBRXRBRARGRXRG
SCHEMBL9653881 0.67 RXRA (0.38) RXRARARBRXRBRARGRXRG
SCHEMBL8522801 0.65 RXRA (0.60) RXRARARBRXRBRARGRXRG
SCHEMBL29565418 0.64 RXRA (0.55) RXRARARBRXRBRARGRXRG
SCHEMBL527839 0.64 RXRA (0.55) RXRARARBRXRBRARGRXRG
SCHEMBL9817816 0.64 RXRA (0.55) RXRARARBRXRBRARGRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7550240-B2 Newtonian, ultrasonic-insensitive charge generating layer dispersion composition and a method for producing the composition EASTMAN KODAK COMPANY (US) 2009-06-23 US claimed
US-7550240-B2 Newtonian, ultrasonic-insensitive charge generating layer dispersion composition and a method for producing the composition EASTMAN KODAK COMPANY (US) 2009-06-23 US disclosed
US-20050266330-A1 Newtonian, ultrasonic-insensitive charge generating layer dispersion composition and a method for producing the composition EASTMAN KODAK COMPANY 2005-12-01 US disclosed
US-5733695-A POLYESTERETHER COPOLYMERS FOR ELECTROGRAPHY EASTMAN KODAK COMPANY (US) 1998-03-31 US disclosed