Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | AGXT | P21549 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4436085 | 1.00 | CYP2D6 (0.44) | CYP2D6HIF1ALOXL2MAOAMAOB | |
| SCHEMBL1287509 | 0.78 | LOXL2 (0.56) | LOXL2MAOBSMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL29594271 | 0.78 | LOXL2 (0.56) | LOXL2MAOBSMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL19550896 | 0.77 | LOXL2 (0.43) | CYP2D6HIF1ALOXL2MAOAMAOB | |
| SCHEMBL252581 | 0.77 | MAPT (0.60) | LOXL2MAOAMAOBSMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL28989961 | 0.77 | LOXL2 (0.55) | LOXL2MAOBSMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL15980824 | 0.76 | CYP2D6 (0.58) | CYP2D6HIF1ALOXL2MAOAMAOB | |
| SCHEMBL398301 | 0.76 | LOXL2 (0.44) | CYP2D6HIF1ALOXL2MAOAMAOB | |
| SCHEMBL2486381 | 0.76 | LOXL2 (0.44) | CYP2D6HIF1ALOXL2MAOAMAOB | |
| Hydrochloric Acid SCHEMBL27927458 | 0.75 | LOXL2 (0.53) | LOXL2MAOBSMN1; SMN2L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023076352-A2 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-05-04 | — | — | WO | disclosed |
| WO-2020219981-A2 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2020-10-29 | — | — | WO | disclosed |
| WO-2020219983-A2 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2020-10-29 | — | — | WO | disclosed |
| EP-2086331-A2 | METHODS OF TREATING NEURONAL DISORDERS USING MNTF PEPTIDES AND ANALOGS THEREOF | Genervon Biopharmaceuticals LLC (US) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008057609-A2 | METHODS OF TREATING NEURONAL DISORDERS USING MNTF PEPTIDES AND ANALOGS THEREOF | GENERVON BIOPHARMACEUTICALS LLC (US) | 2008-05-15 | — | — | WO | disclosed |