SCHEMBL4341007

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2858476	0.78	MAP2K4 (0.68)	ITKTTKNTRK1MAP2K4MAPK3
	SCHEMBL19785181	0.77	HPGD (0.54)	ALDH1A1HPGD
	SCHEMBL5801740	0.77	MAP2K4 (0.65)	TTKNTRK1MAP2K4MAPK8FYN
	SCHEMBL2860913	0.76	MAP2K4 (0.61)	TTKNTRK1MAP2K4MAPK8MAPK3
	Ethylene SCHEMBL27536148	0.76	MAP2K4 (0.65)	ITKTTKNTRK1MAP2K4MAPK3
	SCHEMBL2869247	0.75	MAPK1 (0.54)	TTKNTRK1MAPK3MAPK1CSNK1D
	SCHEMBL2861578	0.75	MAPK1 (0.54)	TTKNTRK1MAPK3MAPK1CSNK1D
	SCHEMBL2869817	0.74	MAP2K4 (0.54)	TTKNTRK1MAP2K4MAPK3MAPK1
	SCHEMBL2868599	0.74	MAP2K4 (0.57)	TTKMAP2K4MAPK8CLK2DYRK1A
	SCHEMBL2859833	0.73	MAPK1 (0.54)	MAPK3MAPK1CSNK1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.