Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL255375 | 0.89 | HPGD (0.67) | HPGDTDP1TSHRALDH1A1OPRM1 | |
| SCHEMBL30786342 | 0.89 | HPGD (0.67) | HPGDTDP1TSHRALDH1A1OPRM1 | |
| SCHEMBL18175995 | 0.82 | HPGD (0.54) | HPGDTDP1TSHRALDH1A1OPRM1 | |
| SCHEMBL21413678 | 0.81 | CDK4 (0.56) | HPGDTSHRALDH1A1OPRM1CES2 | |
| SCHEMBL1003828 | 0.80 | HPGD (0.66) | HPGDTDP1ALDH1A1OPRM1OPRD1 | |
| SCHEMBL12852633 | 0.79 | HPGD (0.51) | HPGDTDP1TSHRALDH1A1LMNA | |
| SCHEMBL13151192 | 0.78 | HPGD (0.50) | HPGDTDP1TSHRALDH1A1LMNA | |
| SCHEMBL20888484 | 0.78 | HPGD (0.50) | HPGDTDP1TSHRALDH1A1LMNA | |
| SCHEMBL29519537 | 0.78 | CES2 (0.46) | TSHROPRM1CES2CES1LMNA | |
| SCHEMBL4341007 | 0.77 | ITK (0.46) | HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10350192-B2 | Lactate dehydrogenase inhibitor and antiepileptic drug containing the same | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2019-07-16 | — | — | US | disclosed |
| US-20180015068-A1 | LACTATE DEHYDROGENASE INHIBITOR AND ANTIEPILEPTIC DRUG CONTAINING THE SAME | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2018-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180015068-A1 | LACTATE DEHYDROGENASE INHIBITOR AND ANTIEPILEPTIC DRUG CONTAINING THE SAME | LDHA, LDHB, ALDH5A1 | HPGD 117/4885TDP1 2018/4885TSHR 4869/4885 |
| US-10350192-B2 | Lactate dehydrogenase inhibitor and antiepileptic drug containing the same | LDHA, LDHB, ALDH5A1 | HPGD 117/4885TDP1 2018/4885TSHR 4869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.