SCHEMBL434144

SCHEMBL434144

CC(N(C)C)C(CCCC(=O)O)(C(=O)O)C(C)N(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
SLC22A6 Q4U2R8 2/20 0.36
PHF8 Q9UPP1 1/20 0.35
KDM2A Q9Y2K7 1/20 0.35
TSHR P16473 5/20 0.34
NFKB1 P19838 1/20 0.34
PMP22 Q01453 1/20 0.34
AKR1B1 P15121 1/20 0.34
GPR84 Q9NQS5 7/20 0.33
PPARG P37231 7/20 0.33
PPARD Q03181 7/20 0.33
PPARA Q07869 7/20 0.33
HDAC11 Q96DB2 5/20 0.33
PTPN1 P18031 3/20 0.33
ALDH1A1 P00352 2/20 0.33
TLR2 O60603 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
FABP4 P15090 2/20 0.33
SLC22A8 Q8TCC7 1/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL169142 0.82 AKR1B1 (0.36) LMNASLC22A6TSHRAKR1B1GPR84
SCHEMBL136592 0.80 LMNA (0.42) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL812764 0.79 LMNA (0.40) LMNASLC22A6KDM2ATSHRNFKB1
SCHEMBL3765877 0.74 LMNA (0.36) LMNASLC22A6TSHRNFKB1PMP22
Citric Acid SCHEMBL28091807 0.74 ALDH1A1 (0.42) LMNATSHRAKR1B1ALDH1A1MEN1
SCHEMBL14809159 0.73 TSHR (0.48) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL14809615 0.73 TSHR (0.48) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL4528638 0.73 AKR1B1 (0.41) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL2504161 0.73 TSHR (0.48) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL14809619 0.73 TSHR (0.48) LMNASLC22A6TSHRNFKB1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3994192-B1 RESISTANT 2K-PUR COATINGS COVESTRO DEUTSCHLAND AG (DE) 2025-04-30 EP disclosed
EP-4277941-B1 COMPOSITIONS CONTAINING URETDIONE GROUPS COVESTRO DEUTSCHLAND AG (DE) 2025-01-01 EP disclosed
EP-4453107-A1 MULTILAYER CONSTRUCTION ON METAL SUBSTRATES BASED ON POLYASPARATE COATINGS Covestro Deutschland AG (DE) 2024-10-30 EP disclosed
WO-2024119532-A1 POLYURETHANE PREPOLYMER COMPOSITION AND PREPARATION METHOD THEREFOR AND USE THEREOF 摩珈(上海)生物科技有限公司 2024-06-13 WO disclosed
EP-4157912-B1 COMPOSITIONS CONTAINING URETDIONE GROUPS CROSSLINKING AT LOW TEMPERATURES COVESTRO DEUTSCHLAND AG (DE) 2024-05-22 EP disclosed
EP-4359459-A1 COATING AGENTS AND COATINGS THAT ARE OBTAINABLE THEREFROM AND HAVE IMPROVED RESISTANCE TO SOILING AND (SELF-)CLEANING PROPERTIES Covestro Deutschland AG (DE) 2024-05-01 EP disclosed
EP-3129353-B1 METHOD FOR MANUFACTURING XYLYLENE DIISOCYANATES IN THE GASEOUS PHASE COVESTRO DEUTSCHLAND AG (DE) 2024-02-28 EP disclosed
EP-3271411-B1 POLYISOCYANATES CONTAINING SILANE GROUPS BASED ON 1,5-DIISOCYANATOPENTANE COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2024-01-10 EP disclosed
EP-4277941-A1 COMPOSITIONS COMPRISING URETDIONES Covestro Deutschland AG (DE) 2023-11-22 EP disclosed
EP-3861039-B1 HYDROGEL COMPOSITIONS OPHTALMIC CIE (FR) 2023-11-01 EP disclosed
EP-2389405-A1 POLYURETHANE CASTING COMPOUNDS Bayer MaterialScience AG (DE) 2011-11-30 EP disclosed
US-20110281965-A1 POLYURETHANE CASTING COMPOUNDS Bayer MateialScience AG (DE) 2011-11-17 US disclosed
US-20110281966-A1 POLYURETHANE SEALING COMPOUNDS COVESTRO DEUTSCHLAND AG (DE) 2011-11-17 US disclosed
US-20110257454-A1 Use of an Additive in the Coupling of Toluene with a Carbon Source FINA TECHNOLOGY, INC. (US) 2011-10-20 US disclosed
US-20110255211-A1 HIGHLY DIELECTRIC FILM DAIKIN INDUSTRIES, LTD. (JP) 2011-10-20 US disclosed
WO-2010083957-A1 POLYURETHANE SEALING COMPOUNDS BAYER MATERIALSCIENCE AG (DE) 2010-07-29 WO disclosed
WO-2010083958-A1 POLYURETHANE CASTING COMPOUNDS BAYER MATERIALSCIENCE AG (DE) 2010-07-29 WO disclosed
US-5196287-A PROCESS FOR PRODUCING ENCAPSULATED PHOTOSENSITIVE COMPOSITION BY ALTERING THE CONCENTRATION OF THE INTERNAL PHASE DURING ENCAPSULATION THE MEAD CORPORATION (US) 1993-03-23 US disclosed
EP-0180749-B1 PROCESS FOR THE PREPARATION OF MOULDED ARTICLES BAYER AG (DE) 1988-06-08 EP disclosed
US-4668734-A Stable dispersions of polyureas and/or polyhydrazo-dicarbonamides in relatively high molecular weight hydroxyl-group containing materials, a process for the production thereof and the use thereof for the production of polyurethane plastics BAYER AKTIENGESELLSCHAFT (DE) 1987-05-26 US disclosed