SCHEMBL812764

SCHEMBL812764

CC(O)C(CCCC(=O)O)(C(=O)O)C(C)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.40
SLC22A6 Q4U2R8 2/20 0.40
TSHR P16473 5/20 0.39
NFKB1 P19838 1/20 0.39
PMP22 Q01453 1/20 0.39
AKR1B1 P15121 1/20 0.38
FFAR4 Q5NUL3 2/20 0.37
FFAR1 O14842 2/20 0.37
PPARG P37231 6/20 0.37
PPARD Q03181 6/20 0.37
PPARA Q07869 6/20 0.37
GPR84 Q9NQS5 5/20 0.37
HDAC11 Q96DB2 5/20 0.37
TET2 Q6N021 3/20 0.37
ALDH1A1 P00352 2/20 0.37
TLR2 O60603 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
FABP4 P15090 2/20 0.37
PTPN1 P18031 2/20 0.37
KDM4A O75164 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10940598 0.92 TSHR (0.46) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL11647058 0.87 CYP1A2 (0.42) LMNASLC22A6FFAR4FFAR1TET2
SCHEMBL136592 0.85 LMNA (0.42) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL9303564 0.80 AKR1B1 (0.40) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL3765877 0.79 LMNA (0.36) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL434144 0.79 LMNA (0.36) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL14809951 0.78 TSHR (0.48) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL14809752 0.78 TSHR (0.48) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL2504161 0.78 TSHR (0.48) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL14809619 0.78 TSHR (0.48) LMNASLC22A6TSHRNFKB1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9296877-B2 Polymer film, retardation film, polarizing plate, liquid crystal display, and compound FUJIFILM CORPORATION (JP) 2016-03-29 US disclosed
US-20140363588-A1 POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND COMPOUND FUJIFILM CORPORATION (JP) 2014-12-11 US disclosed
US-20140053755-A1 Cellulose Acylate Film, Retardation Film, Polarizer and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2014-02-27 US disclosed
US-20130216733-A1 OPTICAL FILM AND ITS PRODUCTION METHOD, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2013-08-22 US disclosed
US-8465673-B2 Humidity dependence improver for polymer film, polymer film, protective film for polarizer, retardation film, polarizer, and liquid crystal display device FUJIFILM CORPORATION (JP) 2013-06-18 US disclosed
US-20130027634-A1 LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2013-01-31 US disclosed
US-8293341-B2 Cellulose ester film, retardation film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-10-23 US disclosed
US-8263195-B2 Cellulose ester film, optically compensatory film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-09-11 US disclosed
US-20120204757-A1 Cellulose Acylate Film, Retardation Film, Polarizer and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2012-08-16 US disclosed
US-20120177848-A1 CELLULOSE ACYLATE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-07-12 US disclosed
US-20090286016-A1 CELLULOSE ESTER FILM, RETARDATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-11-19 US disclosed
US-20080035024-A1 Aqueous PU dispersions with improved adhesion COVESTRO DEUTSCHLAND AG (DE) 2008-02-14 US disclosed
US-4861826-A Aqueous polyurethane adhesive dispersions BASF AKTIENGESELLSCHAFT (DE) 1989-08-29 US disclosed
US-4522998-A VINYL ESTER, ALPHA-OLEFIN, AND VINYLCYCLOPROPANEDICARBOXYLATE POLYESTER NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1985-06-11 US disclosed
US-4522999-A WITH UNSATURATED ESTER NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1985-06-11 US disclosed
US-4444960-A POLYESTER, POLYSULFONATE OCCIDENTAL CHEMICAL CORPORATION (US) 1984-04-24 US disclosed
US-4321406-A Vinylcyclopropane monomers and oligomers EMERY INDUSTRIES, INC. (US) 1982-03-23 US disclosed
US-4256625-A PERFLUOROALKENYLOXY, N-PHOSPHATOALKYL-SULFAMOYL-BENZENE SURFACTANT HOOKER CHEMICALS & PLASTICS CORP. (US) 1981-03-17 US disclosed
US-4251429-A COMPRISING POLYPHENYLENE SULFIDE AND AN AROMATIC POLYESTER HOOKER CHEMICALS & PLASTICS CORP. (US) 1981-02-17 US disclosed
US-3959200-A HUMAN EARPLUGS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140363588-A1 POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND COMPOUND PYM1, CNKSR1, MYB LMNA 1435/4885SLC22A6 3079/4885TSHR 778/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.