Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NQO2 | P16083 | 7/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL4334323 | 0.84 | MAPT (0.35) | ALDH1A1TSHRMAPT | |
| Toluene SCHEMBL27566737 | 0.58 | ACHE (0.61) | POLBKDM4EALDH1A1MEN1NPC1 | |
| Lithium Ion SCHEMBL4340768 | 0.58 | — | — | |
| Lithium Ion SCHEMBL4334276 | 0.58 | — | — | |
| Chlorobenzene SCHEMBL28228223 | 0.56 | TSHR (0.58) | POLBKDM4EMEN1LMNAKMT2A | |
| Lithium Ion SCHEMBL3056860 | 0.54 | — | — | |
| Lithium Ion SCHEMBL10842928 | 0.54 | — | — | |
| Phenylboronic Acid SCHEMBL28179340 | 0.54 | ENPP2 (0.67) | — | |
| SCHEMBL1408391 | 0.54 | POLB (1.00) | POLBNQO2KDM4EALDH1A1MEN1 | |
| Quinoline SCHEMBL27543949 | 0.54 | ALDH1A1 (0.81) | POLBKDM4EALDH1A1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1442489-B1 | NON-AQUEOUS ELECTROLYTES FOR LITHIUM ELECTROCHEMICAL CELLS | YARDNEY TECH PROD (US) | 2009-09-16 | — | — | EP | claimed |
| JP-2005536832-A | — | — | 2005-12-02 | — | — | JP | claimed |
| US-6852446-B2 | Non-aqueous electrolytes for lithium electrochemical cells | YARDNEY TECHNICAL PRODUCTS, INC. (US) | 2005-02-08 | — | — | US | claimed |
| EP-1442489-A2 | NON-AQUEOUS ELECTROLYTES FOR LITHIUM ELECTROCHEMICAL CELLS | YARDNEY TECHNICAL PRODUCTS, INC. (US) | 2004-08-04 | — | — | EP | claimed |
| US-20030108800-A1 | Non-aqueous electrolytes for lithium electrochemical cells | DUKE FINANCE SUBSIDIARY HOLDINGS, LLC | 2003-06-12 | — | — | US | claimed |
| WO-2003043102-A2 | NON-AQUEOUS ELECTROLYTES FOR LITHIUM ELECTROCHEMICAL CELLS | YARDNEY TECHNICAL PRODUCTS, INC. (US) | 2003-05-22 | — | — | WO | claimed |