SCHEMBL4344332

SCHEMBL4344332

CC(C)(C)c1ccc2c(c1)C(=O)c1ccccc1C2=O.O=C1c2ccc(Cl)cc2C(=O)c2ccc(Cl)cc21

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.80
RAB9A P51151 5/20 0.80
ALDH1A1 P00352 4/20 0.80
CASP3 P42574 2/20 0.80
SENP8 Q96LD8 2/20 0.80
SENP7 Q9BQF6 2/20 0.80
SENP6 Q9GZR1 2/20 0.80
L3MBTL1 Q9Y468 2/20 0.80
PLA2G1B P04054 1/20 0.80
NFKB1 P19838 1/20 0.80
NFKB2 Q00653 1/20 0.80
RELA Q04206 1/20 0.80
ATG4B Q9Y4P1 1/20 0.80
S100A4 P26447 2/20 0.62
SMN1; SMN2 Q16637 4/20 0.57
MAPK1 P28482 3/20 0.57
LMNA P02545 2/20 0.57
ATM Q13315 1/20 0.57
ITGA1 P56199 1/20 0.49
ELANE P08246 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL36613 0.89 NPC1 (1.00) NPC1RAB9AALDH1A1CASP3SENP8
SCHEMBL29402468 0.89 NPC1 (1.00) NPC1RAB9AALDH1A1CASP3SENP8
Dichlon SCHEMBL18227115 0.88 NPC1 (0.83) NPC1RAB9AALDH1A1CASP3SENP8
SCHEMBL867392 0.88 NPC1 (0.96) NPC1RAB9AALDH1A1CASP3SENP8
SCHEMBL13439536 0.84 NPC1 (0.89) NPC1RAB9AALDH1A1CASP3SENP8
SCHEMBL5724160 0.84 NPC1 (0.88) NPC1RAB9AALDH1A1CASP3SENP8
SCHEMBL13433263 0.84 NPC1 (0.88) NPC1RAB9AALDH1A1CASP3SENP8
SCHEMBL155593 0.84 S100A4 (0.87) NPC1RAB9AALDH1A1CASP3SENP8
SCHEMBL29378883 0.84 S100A4 (0.87) NPC1RAB9AALDH1A1CASP3SENP8
Anthraquinone SCHEMBL10531854 0.84 S100A4 (0.87) NPC1RAB9AALDH1A1CASP3SENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8872099-B2 Solid-state image sensor including a light-shielding color filter formed from a photosensitive resin composition, photosensitive resin composition and method of producing a light-shielding color filter FUJIFILM CORPORATION (JP) 2014-10-28 US disclosed
US-20090236509-A1 PHOTOSENSITIVE RESIN COMPOSITION, LIGHT-SHIELDING COLOR FILTER, METHOD OF PRODUCING THE SAME AND SOLID-STATE IMAGE SENSOR FUJIFILM CORPORATION (JP) 2009-09-24 US disclosed