Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.96 |
| ▸ | RAB9A | P51151 | 7/20 | 0.96 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.96 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.96 |
| ▸ | ATG4B | Q9Y4P1 | 3/20 | 0.96 |
| ▸ | CASP3 | P42574 | 2/20 | 0.96 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.96 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.96 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.96 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.96 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.96 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.96 |
| ▸ | RELA | Q04206 | 1/20 | 0.96 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | ATM | Q13315 | 2/20 | 0.66 |
| ▸ | ELANE | P08246 | 1/20 | 0.53 |
| ▸ | PARG | Q86W56 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29402468 | 0.98 | NPC1 (1.00) | NPC1RAB9AALDH1A1PLA2G1BATG4B | |
| SCHEMBL36613 | 0.98 | NPC1 (1.00) | NPC1RAB9AALDH1A1PLA2G1BATG4B | |
| SCHEMBL13439536 | 0.96 | NPC1 (0.89) | NPC1RAB9AALDH1A1PLA2G1BATG4B | |
| SCHEMBL15383586 | 0.92 | NPC1 (0.81) | NPC1RAB9AALDH1A1PLA2G1BATG4B | |
| SCHEMBL29163430 | 0.92 | NPC1 (0.81) | NPC1RAB9AALDH1A1PLA2G1BATG4B | |
| SCHEMBL13433263 | 0.92 | NPC1 (0.88) | NPC1RAB9AALDH1A1PLA2G1BATG4B | |
| SCHEMBL5724160 | 0.92 | NPC1 (0.88) | NPC1RAB9AALDH1A1PLA2G1BATG4B | |
| SCHEMBL2706394 | 0.92 | ALDH1A1 (0.80) | NPC1RAB9AALDH1A1PLA2G1BATG4B | |
| SCHEMBL30552387 | 0.92 | ALDH1A1 (0.80) | NPC1RAB9AALDH1A1PLA2G1BATG4B | |
| Dichlon SCHEMBL18227115 | 0.89 | NPC1 (0.83) | NPC1RAB9AALDH1A1PLA2G1BATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3238286-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2024-01-17 | — | — | EP | disclosed |
| CN-112390771-B | Novel hole transport material with excellent performance and organic electroluminescent device containing same | 南京高光半导体材料有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-113652705-B | Method for synthesizing fluorenone through catalytic electrolysis of N-hydroxyphthalimide | 北京工业大学 | 2022-07-22 | — | — | CN | disclosed |
| CN-113652705-A | Method for synthesizing fluorenone by catalyzing and electrolyzing N-hydroxyphthalimide | 北京工业大学 | 2021-11-16 | — | — | CN | disclosed |
| US-10781183-B2 | Small molecule inducers of reactive oxygen species and inhibitors of mitochondrial activity | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2020-09-22 | — | — | US | disclosed |
| US-10777750-B2 | Heterocyclic spiro compounds | BASF SE (DE) | 2020-09-15 | — | — | US | disclosed |
| US-10665790-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2020-05-26 | — | — | US | disclosed |
| US-20190308942-A1 | SMALL MOLECULE INDUCERS OF REACTIVE OXYGEN SPECIES AND INHIBITORS OF MITOCHONDRIAL ACTIVITY | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2019-10-10 | — | — | US | disclosed |
| CN-105778891-B | Organic photoelectrical material, preparation method and the organic electroluminescence device including the organic material | 中节能万润股份有限公司 | 2019-03-19 | — | — | CN | disclosed |
| US-10224492-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2019-03-05 | — | — | US | disclosed |
| US-8293715-B2 | 10a-Azalide compound crosslinked at 10a- and 12-positions | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-10-23 | — | — | US | disclosed |
| US-20120074336-A1 | LIGHT-DRIVEN ROTARY MOLECULAR MOTORS | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE (US) | 2012-03-29 | — | — | US | disclosed |
| US-20110237784-A1 | 10A-AZALIDE COMPOUND CROSSLINKED AT 10A- AND 12-POSITIONS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2011-09-29 | — | — | US | disclosed |
| US-20110166141-A1 | CATHEPSIN S INHIBITORS | DCB-USA, LLC (US) | 2011-07-07 | — | — | US | disclosed |
| US-7964722-B2 | Light-driven rotary molecular motors | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (US) | 2011-06-21 | — | — | US | disclosed |
| US-7964722-B2 | Light-driven rotary molecular motors | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (US) | 2011-06-21 | — | — | US | disclosed |
| US-20110077394-A1 | LIGHT-DRIVEN ROTARY MOLECULAR MOTORS | NATIONAL SCIENCE FOUNDATION | 2011-03-31 | — | — | US | disclosed |
| US-20110077394-A1 | LIGHT-DRIVEN ROTARY MOLECULAR MOTORS | NATIONAL SCIENCE FOUNDATION | 2011-03-31 | — | — | US | disclosed |
| US-7691848-B2 | Pyrrolobenzodiazepine arylcarboxamides and derivatives thereof as follicle-stimulating hormone receptor antagonists | WYETH (US) | 2010-04-06 | — | — | US | disclosed |
| US-6162824-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | ALLELIX NEUROSCIENCE INC. | 2000-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237784-A1 | 10A-AZALIDE COMPOUND CROSSLINKED AT 10A- AND 12-POSITIONS | DCLRE1A, AZI2, CHD9 | NPC1 3703/4885RAB9A 58/4885ALDH1A1 2376/4885 |
| US-20190308942-A1 | SMALL MOLECULE INDUCERS OF REACTIVE OXYGEN SPECIES AND INHIBITORS OF MITOCHONDRIAL ACTIVITY | SQOR, MAVS, TFAM | NPC1 3235/4885RAB9A 865/4885ALDH1A1 1628/4885 |
| US-10665790-B2 | Materials for electronic devices | SDHB, SDHA, ETFB | NPC1 3354/4885RAB9A 2932/4885ALDH1A1 150/4885 |
| US-20110077394-A1 | LIGHT-DRIVEN ROTARY MOLECULAR MOTORS | CCNA2, CCNO, SCO2 | NPC1 4541/4885RAB9A 2397/4885ALDH1A1 4255/4885 |
| US-10781183-B2 | Small molecule inducers of reactive oxygen species and inhibitors of mitochondrial activity | SQOR, MAVS, TFAM | NPC1 3235/4885RAB9A 865/4885ALDH1A1 1628/4885 |
| US-10777750-B2 | Heterocyclic spiro compounds | NES, KCNC1, HCN4 | NPC1 2116/4885RAB9A 1935/4885ALDH1A1 383/4885 |
| US-20110166141-A1 | CATHEPSIN S INHIBITORS | CTSS, CTSV, CTSB | NPC1 738/4885RAB9A 561/4885ALDH1A1 2734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.