Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29713847 | 0.89 | ALDH1A1 (0.90) | ALDH1A1CYP3A4TDP1TAAR1CYP1A2 | |
| Biphenyl SCHEMBL895675 | 0.89 | ALDH1A1 (0.90) | ALDH1A1CYP3A4TDP1TAAR1CYP1A2 | |
| SCHEMBL18674172 | 0.89 | ALDH1A1 (0.90) | ALDH1A1CYP3A4TDP1TAAR1CYP1A2 | |
| Tannin Pyrogallol SCHEMBL21448 | 0.89 | ALDH1A1 (0.90) | ALDH1A1CYP3A4TDP1TAAR1CYP1A2 | |
| SCHEMBL1991754 | 0.89 | ALDH1A1 (0.90) | ALDH1A1CYP3A4TDP1TAAR1CYP1A2 | |
| SCHEMBL827097 | 0.89 | ALDH1A1 (0.90) | ALDH1A1CYP3A4TDP1TAAR1CYP1A2 | |
| Tannin Pyrogallol SCHEMBL11689471 | 0.89 | ALDH1A1 (0.90) | ALDH1A1CYP3A4TDP1TAAR1CYP1A2 | |
| SCHEMBL143471 | 0.89 | ALDH1A1 (0.90) | ALDH1A1CYP3A4TDP1TAAR1CYP1A2 | |
| SCHEMBL2637802 | 0.89 | ALDH1A1 (0.90) | ALDH1A1CYP3A4TDP1TAAR1CYP1A2 | |
| Tannin Pyrogallol SCHEMBL3486430 | 0.89 | ALDH1A1 (0.90) | ALDH1A1CYP3A4TDP1TAAR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116854777-A | Biological image probe unit, biological image nano probe, preparation method and application | 中国科学院苏州纳米技术与纳米仿生研究所 | 2023-10-10 | — | — | CN | claimed |
| CN-102405039-A | Cosmetic or dermatological composition comprising a polymer containing linking groups, and cosmetic treatment method | OREAL | 2012-04-04 | — | — | CN | claimed |
| WO-2012012366-A1 | PESTICIDAL 3-(ARYLOXY)AZACYCLOALKANES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-01-26 | — | — | WO | claimed |
| EP-1188744-B1 | Process for producing optically active 1H-3-aminopyrrolidine and derivatives thereof | MITSUBISHI CHEM CORP (JP) | 2005-11-02 | — | — | EP | claimed |
| US-6531594-B2 | Reacting an amino-protected aspartic anhydride with an aralkylamine, cyclodehydration to obtain a 1-aralkyl-3-(protected amino)pyrrolidine-2,5-dione, reducing carbonyl groups, then hydrogenolysis; carbapenems, drug intermediate | MITSUBISHI CHEMICAL CORPORATION (JP) | 2003-03-11 | — | — | US | claimed |
| US-20020042523-A1 | Process for producing 1H-3-aminopyrrolidine and derivatives thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-04-11 | — | — | US | claimed |
| EP-1188744-A1 | Process for producing 1H-3-aminopyrrolidine and derivatives thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-03-20 | — | — | EP | claimed |
| EP-0442399-B1 | Wholly aromatic polyamides, process for preparing them and moulded articles thereof | HOECHST AG (DE) | 1995-05-10 | — | — | EP | claimed |
| EP-0424860-B1 | Wholly aromatic polyamides, process for their preparation and products therefrom | HOECHST AG (DE) | 1993-12-01 | — | — | EP | claimed |
| EP-0364892-B1 | WHOLLY AROMATIC POLYAMIDES, PROCESS FOR PRODUCING THE SAME AND SHAPED ARTICLES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-09 | — | — | EP | claimed |
| EP-0364891-B1 | WHOLLY AROMATIC POLYAMIDES, PROCESS FOR PRODUCING THE SAME AND SHAPED ARTICLES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-09 | — | — | EP | claimed |
| EP-0364893-B1 | WHOLLY AROMATIC POLYAMIDES, PROCESS FOR PRODUCING THE SAME AND SHAPED ARTICLES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-05-19 | — | — | EP | claimed |
| US-5097015-A | Fibers, filaments, films and sheets | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-17 | — | — | US | claimed |
| EP-0442399-A2 | Wholly aromatic polyamides, process for preparing them and moulded articles thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-21 | — | — | EP | claimed |
| EP-0424860-A2 | Wholly aromatic polyamides, process for their preparation and products therefrom | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-02 | — | — | EP | claimed |
| EP-0396020-A2 | Fibrous material from homogeneous alloys of aromatic polyamides and poly-N-vinyl-pyrrolidone, process for their preparation and application | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-11-07 | — | — | EP | claimed |
| EP-0364891-A2 | Wholly aromatic polyamides, process for producing the same and shaped articles | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-04-25 | — | — | EP | claimed |
| EP-0364893-A2 | Wholly aromatic polyamides, process for producing the same and shaped articles | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-04-25 | — | — | EP | claimed |
| EP-0364892-A2 | Wholly aromatic polyamides, process for producing the same and shaped articles | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-04-25 | — | — | EP | claimed |
| US-3992143-A | DISAZO AND TRIAZO DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020042523-A1 | Process for producing 1H-3-aminopyrrolidine and derivatives thereof | ASPH, ALDH7A1, AASDHPPT | ALDH1A1 355/4885CYP3A4 2041/4885TDP1 3470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.