Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | GPR3 | P46089 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3735430 | 0.80 | LMNA (0.53) | LMNAPDE10ANPSR1ALDH1A1MAPK1 | |
| SCHEMBL4355754 | 0.78 | LMNA (0.56) | LMNAPDE10ANPSR1ALDH1A1MAPK1 | |
| SCHEMBL16424551 | 0.78 | LMNA (0.51) | LMNAPDE10ANPSR1ALDH1A1MAPK1 | |
| SCHEMBL14473916 | 0.78 | LMNA (0.51) | LMNAPDE10ANPSR1ALDH1A1MAPK1 | |
| SCHEMBL7074713 | 0.77 | PDE10A (0.56) | LMNAPDE10ANPSR1ALDH1A1MAPK1 | |
| SCHEMBL29364974 | 0.75 | MAPT (0.62) | ALDH1A1MAPTCYP1A2KDM4EHPGD | |
| SCHEMBL103601 | 0.75 | MAPT (0.62) | ALDH1A1MAPTCYP1A2KDM4EHPGD | |
| SCHEMBL22342229 | 0.75 | ALDH1A1 (0.55) | LMNAPDE10ANPSR1ALDH1A1MAPK1 | |
| SCHEMBL11328150 | 0.75 | LMNA (0.49) | LMNAPDE10ANPSR1ALDH1A1MAPK1 | |
| SCHEMBL12775683 | 0.75 | LMNA (0.49) | LMNAPDE10ANPSR1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1961733-B1 | METHOD FOR SELECTIVELY PRODUCING PRIMARY AMINE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2014-08-20 | — | — | EP | disclosed |
| CN-101370765-B | Method for selectively producing primary amine | SUMITOMO CHEMICAL CO | 2013-03-13 | — | — | CN | disclosed |
| US-8269044-B2 | Method for selectively producing primary amine compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-09-18 | — | — | US | disclosed |
| US-20090281325-A1 | METHOD FOR SELECTIVELY PRODUCING PRIMARY AMINE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-11-12 | — | — | US | disclosed |
| CN-101370765-A | Method for selectively producing primary amine | SUMITOMO CHEMICAL CO (JP) | 2009-02-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281325-A1 | METHOD FOR SELECTIVELY PRODUCING PRIMARY AMINE COMPOUND | NAT1, AADAC, AOC3 | LMNA 2739/4885PDE10A 1327/4885NPSR1 1257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.