Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | FASN | P49327 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.31 |
| ▸ | SPR | P35270 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4350380 | 0.87 | FASN (0.34) | GAAFASNPIK3C3HSP90AA1HCRTR1 | |
| SCHEMBL4342604 | 0.74 | GAA (0.39) | GAAALOX15KMT2AHCRTR1HCRTR2 | |
| SCHEMBL28286272 | 0.68 | ALDH1A1 (0.57) | GAAALDH1A1 | |
| SCHEMBL4349456 | 0.68 | HPGD (0.40) | GAAKMT2AALDH1A1 | |
| SCHEMBL4350146 | 0.68 | TDP1 (0.51) | GAAKMT2AALDH1A1 | |
| SCHEMBL4353500 | 0.66 | ATM (0.44) | GAAKMT2AALDH1A1 | |
| SCHEMBL4342450 | 0.65 | KDM4E (0.48) | GAAKMT2AHSP90AA1ALDH1A1 | |
| SCHEMBL4345832 | 0.63 | GAA (0.36) | GAAALOX15KMT2APIK3C3SPR | |
| SCHEMBL4349007 | 0.63 | KMT2A (0.41) | GAAALOX15KMT2AALDH1A1POLB | |
| SCHEMBL4354896 | 0.62 | HPGD (0.34) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2088149-A1 | PHARMACOLOGICALLY ACTIVE N,N'-SUBSTITUTED 3,7-DIAZABICYCLO Ý3.3.1¨NONANES, PHARMACEUTICAL COMPOSITIONS BASED THEREON AND A METHOD FOR THE USE THEREOF | Institute of Physiologically active compunds of the Russian Academy of Sciences (IPAC RAN) (RU) | 2009-08-12 | — | — | EP | claimed |
| EP-2088149-A1 | PHARMACOLOGICALLY ACTIVE N,N'-SUBSTITUTED 3,7-DIAZABICYCLO Ý3.3.1¨NONANES, PHARMACEUTICAL COMPOSITIONS BASED THEREON AND A METHOD FOR THE USE THEREOF | Institute of Physiologically active compunds of the Russian Academy of Sciences (IPAC RAN) (RU) | 2009-08-12 | — | — | EP | disclosed |