SCHEMBL4346969

SCHEMBL4346969

[Li]C1(C(=O)O)CC=Cc2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
HDAC4 P56524 5/20 0.35
AKR1C1 Q04828 1/20 0.34
KIF11 P52732 3/20 0.33
HSD11B1 P28845 1/20 0.32
CRHBP P24387 1/20 0.30
CRHR2 Q13324 1/20 0.30
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9302017 0.79 THRB (0.35) THRBTDP1HDAC4AKR1C1KIF11
SCHEMBL9155004 0.79 THRB (0.37) THRBTDP1HDAC4AKR1C1KIF11
Hydrochloric Acid SCHEMBL28933194 0.77 THRB (0.36) THRBTDP1HDAC4AKR1C1KIF11
SCHEMBL461337 0.77 THRB (0.40) THRBTDP1HDAC4AKR1C1KIF11
Oxalic Acid SCHEMBL29053840 0.77 THRB (0.36) THRBTDP1HDAC4AKR1C1KIF11
SCHEMBL28462695 0.76 ALDH1A1 (0.34) HDAC4
SCHEMBL9899733 0.76 THRB (0.35) THRBTDP1HDAC4AKR1C1KIF11
SCHEMBL8491987 0.76 TDP1 (0.35) THRBTDP1HDAC4AKR1C1KIF11
SCHEMBL8489491 0.76 THRB (0.35) THRBTDP1HDAC4AKR1C1KIF11
SCHEMBL7064134 0.74 KDM4E (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115466425-B Chiral phenyl ester polymer crosslinked film and preparation method and application thereof 苏州大学 2024-01-30 CN disclosed
EP-3106506-A1 STAR POLYMER LUBRICATING COMPOSITION The Lubrizol Corporation (US) 2016-12-21 EP disclosed
EP-2021442-B1 STAR POLYMER LUBRICATING COMPOSITION LUBRIZOL CORP (US) 2016-08-17 EP disclosed
EP-2024469-A2 STAR POLYMER LUBRICATING COMPOSITION THE LUBRIZOL CORPORATION (US) 2009-02-18 EP disclosed
EP-2021442-A1 STAR POLYMER LUBRICATING COMPOSITION THE LUBRIZOL CORPORATION (US) 2009-02-11 EP disclosed
WO-2007127661-A1 STAR POLYMER LUBRICATING COMPOSITION THE LUBRIZOL CORPORATION (US) 2007-11-08 WO disclosed
WO-2007127615-A2 STAR POLYMER LUBRICATING COMPOSITION THE LUBRIZOL CORPORATION (US) 2007-11-08 WO disclosed