SCHEMBL434710

SCHEMBL434710

Cc1cc(Cl)c(N)cc1N

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.58
CYP3A4 P08684 6/20 0.52
TSHR P16473 5/20 0.52
MAPK1 P28482 2/20 0.52
CD44 P16070 1/20 0.52
ALDH1A1 P00352 6/20 0.48
CYP1A2 P05177 1/20 0.48
ALOX15 P16050 1/20 0.48
CASP7 P55210 1/20 0.48
HIF1A Q16665 1/20 0.48
HSD17B10 Q99714 1/20 0.48
NPC1 O15118 2/20 0.44
TERT O14746 1/20 0.41
TDP1 Q9NUW8 2/20 0.40
CASP1 P29466 1/20 0.40
TP53 P04637 1/20 0.40
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
ATM Q13315 1/20 0.37
UHRF1 Q96T88 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29683620 0.89 GAA (0.67) GAACYP3A4TSHRMAPK1CD44
SCHEMBL2026149 0.89 GAA (0.67) GAACYP3A4TSHRMAPK1CD44
Hydrochloric Acid SCHEMBL8647124 0.86 CD44 (0.64) GAACYP3A4TSHRMAPK1CD44
Hydrochloric Acid SCHEMBL8647129 0.86 CD44 (0.64) GAACYP3A4TSHRMAPK1CD44
SCHEMBL6944526 0.86 CD44 (0.62) GAACYP3A4TSHRMAPK1CD44
SCHEMBL16282614 0.86 CD44 (0.62) GAACYP3A4TSHRMAPK1CD44
SCHEMBL203360 0.83 CD44 (0.75) GAACYP3A4TSHRMAPK1CD44
SCHEMBL8341703 0.83 CD44 (0.75) GAACYP3A4TSHRMAPK1CD44
SCHEMBL3365801 0.82 GAA (0.50) GAACYP3A4TSHRMAPK1CD44
SCHEMBL3646364 0.79 CD44 (0.48) GAACYP3A4TSHRMAPK1CD44

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 313 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11021606-B2 Multilayer film for electronic circuitry applications E I DU PONT DE NEMOURS AND COMPANY (US) 2021-06-01 US claimed
US-20130171459-A1 POLYAMIC ACID RESIN SOLUTION CONTAINING INTERPENETRATING POLYMER AND LAMINATE USING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2013-07-04 US claimed
EP-1292272-B1 OXIDATION DYE FOR HAIR HENKEL KGAA (DE) 2007-03-07 EP claimed
US-20070009751-A1 Polyamic acid resin composition modified with laminate nanometer silica sheet and polyimide prepared therefrom CHANG CHUN PLASTICS CO., LTD. (TW) 2007-01-11 US claimed
US-7005163-B2 Organic-inorganic hybrid film material and its fabrication CHANG CHUN PLASTICS CO., LTD. (TW) 2006-02-28 US claimed
EP-1309540-B1 OXIDIZING COLORANT HENKEL KGAA (DE) 2005-11-02 EP claimed
EP-1431984-A1 Polymer resistor composition having a substantially neutral temperature coefficient of resistance and methods and compositions relating thereto E. I. du Pont de Nemours and Company (US) 2004-06-23 EP claimed
US-20040113127-A1 Resistor compositions having a substantially neutral temperature coefficient of resistance and methods and compositions relating thereto E.I. DU PONT DE NEMOURS AND COMPANY 2004-06-17 US claimed
US-20040110014-A1 Organic-inorganic hybrid film material and its fabrication CHANG CHUN PLASTICS CO., LTD. (TW) 2004-06-10 US claimed
EP-1309540-A1 OXIDIZING COLORANT Henkel Kommanditgesellschaft auf Aktien (DE) 2003-05-14 EP claimed
EP-1292272-A2 OXIDISED HAIR DYE Henkel Kommanditgesellschaft auf Aktien (DE) 2003-03-19 EP claimed
WO-2002010118-A1 OXIDIZING COLORANT HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-02-07 WO claimed
WO-2001097766-A2 OXIDISED HAIR DYE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-27 WO claimed
EP-0284803-B1 Novel soluble polymidesiloxanes and methods for their preparation and use OCCIDENTAL CHEM CO (US) 1998-07-15 EP claimed
US-4973645-A BLOCK POLYMERS, OXYDIPHTHALIC ANHYDRIDE, ELECTRONIC APPLICATIONS OCCIDENTAL CHEMICAL CORPORATION (US) 1990-11-27 US claimed
EP-0284803-A2 Novel soluble polymidesiloxanes and methods for their preparation and use Occidental Chemical Corporation (US) 1988-10-05 EP claimed
CN-111087617-B Low haze polymer film and electronic device 杜邦电子公司 2024-03-01 CN disclosed
US-20240052104-A1 DICARBONYL HALIDES, POLYMER COMPOSITIONS AND FILMS MADE THEREFROM U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-02-15 US disclosed
US-4523004-A 1,4-BUTANEDIOL AND MONOSUBSTITUTED TOLUENE DIAMINE GAF CORPORATION (US) 1985-06-11 US disclosed
EP-0102203-A1 Diamine/diol chain extender blends for RIM process GAF CORPORATION (US) 1984-03-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240052104-A1 DICARBONYL HALIDES, POLYMER COMPOSITIONS AND FILMS MADE THEREFROM PUF60, PICALM, PARG GAA 2583/4885CYP3A4 3952/4885TSHR 4721/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.