Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD44 | P16070 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9634914 | 0.86 | CD44 (0.75) | CD44CYP3A4TSHRMAPK1GAA | |
| SCHEMBL29683620 | 0.86 | GAA (0.67) | CD44CYP3A4TSHRMAPK1GAA | |
| SCHEMBL434710 | 0.86 | GAA (0.58) | CD44CYP3A4TSHRMAPK1GAA | |
| SCHEMBL203360 | 0.86 | CD44 (0.75) | CD44CYP3A4TSHRMAPK1GAA | |
| SCHEMBL2026149 | 0.86 | GAA (0.67) | CD44CYP3A4TSHRMAPK1GAA | |
| SCHEMBL29739478 | 0.86 | CD44 (0.75) | CD44CYP3A4TSHRMAPK1GAA | |
| Hydrochloric Acid SCHEMBL8647129 | 0.83 | CD44 (0.64) | CD44CYP3A4TSHRMAPK1GAA | |
| Hydrochloric Acid SCHEMBL8647124 | 0.83 | CD44 (0.64) | CD44CYP3A4TSHRMAPK1GAA | |
| SCHEMBL10524409 | 0.83 | CD44 (0.56) | CD44CYP3A4TSHRMAPK1GAA | |
| SCHEMBL1770635 | 0.81 | CD44 (0.54) | CD44CYP3A4TSHRMAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230373940-A1 | CARBOXYLIC DIARYLTHIAZEPINEAMINES AND USES THEREOF | KURES, INC. | 2023-11-23 | — | — | US | disclosed |
| US-20230373940-A1 | CARBOXYLIC DIARYLTHIAZEPINEAMINES AND USES THEREOF | KURES, INC. | 2023-11-23 | — | — | US | disclosed |
| US-11787772-B2 | Carboxylic diarythiazepineamines as mixed mu- and delta-opioid receptor agonists | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-10-17 | — | — | US | disclosed |
| US-20230242548-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-08-03 | — | — | US | disclosed |
| WO-2021053158-A1 | NOVEL HISTONE METHYLTRANSFERASE INHIBITORS | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2021-03-25 | — | — | WO | disclosed |
| US-9655965-B2 | Radiosensitizer compounds for use in combination with radiation | Lu qing-bin (CA) | 2017-05-23 | — | — | US | disclosed |
| EP-2763990-B1 | PYRROLOPYRAZINE KINASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2017-02-22 | — | — | EP | disclosed |
| EP-2763990-B1 | PYRROLOPYRAZINE KINASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2017-02-22 | — | — | EP | disclosed |
| EP-2855453-B1 | BENZIMIDAZOLE-PROLINE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2016-12-07 | — | — | EP | disclosed |
| US-20160235743-A1 | NON-PLATINUM-BASED ANTI-CANCER COMPOUNDS FOR USE IN TARGETED CHEMOTHERAPY | Lu qing-bin (CA) | 2016-08-18 | — | — | US | disclosed |
| US-4193937-A | DECHLORINATION OF CHLOROANILINES, SELECTIVE HYDROGENATION CATALYSTS OF NOBLE METAL AND SULFUR | BAYER AKTIENGESELLSCHAFT (DE) | 1980-03-18 | — | — | US | disclosed |
| US-4141718-A | ANTIGROWTH AGENTS FOR PLANTS | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |
| US-4139530-A | CATIONIC DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-13 | — | — | US | disclosed |
| EP-0000050-A1 | Derivatives of 4-(2-chloro-4-nitrophenoxy)-phenoxyalkanecarboxylic acids, method for their preparation and their use as herbicides. | BAYER AG (DE) | 1978-12-20 | — | — | EP | disclosed |
| US-4101575-A | FUNGICIDES, BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1978-07-18 | — | — | US | disclosed |
| US-4085268-A | Disubstituted s-triazines | ARMSTRONG CORK COMPANY (US) | 1978-04-18 | — | — | US | disclosed |
| US-4055559-A | ACETYLACETANILIDO | CIBA-GEIGY CORPORATION (US) | 1977-10-25 | — | — | US | disclosed |
| US-4036850-A | FUNGICIDES, HERBICIDES, BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | disclosed |
| US-3975534-A | Pharmaceutical compositions useful for treating tick infestation in animals which contain 2-aryliminopyrrolidines or their salts as the active agent | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-17 | — | — | US | disclosed |
| US-3934019-A | FUNGICIDE, INSECTICIDE, MITICIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787772-B2 | Carboxylic diarythiazepineamines as mixed mu- and delta-opioid receptor agonists | OPRD1, OPRM1, OPRK1 | CD44 3296/4885CYP3A4 500/4885TSHR 510/4885 |
| US-20230373940-A1 | CARBOXYLIC DIARYLTHIAZEPINEAMINES AND USES THEREOF | CDKL5, KMT5A, CDKL1 | CD44 3730/4885CYP3A4 2371/4885TSHR 4254/4885 |
| US-20160235743-A1 | NON-PLATINUM-BASED ANTI-CANCER COMPOUNDS FOR USE IN TARGETED CHEMOTHERAPY | TOP2B, POLR2B, RB1 | CD44 1728/4885CYP3A4 2840/4885TSHR 1025/4885 |
| US-20230242548-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | KRAS, HRAS, NRAS | CD44 68/4885CYP3A4 4840/4885TSHR 4752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.