Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD44 | P16070 | 1/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.60 |
| ▸ | TSHR | P16473 | 4/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9634914 | 0.89 | CD44 (0.75) | CD44CYP3A4TSHRMAPK1ALDH1A1 | |
| SCHEMBL29739478 | 0.89 | CD44 (0.75) | CD44CYP3A4TSHRMAPK1ALDH1A1 | |
| SCHEMBL6944526 | 0.86 | CD44 (0.62) | CD44CYP3A4TSHRMAPK1ALDH1A1 | |
| SCHEMBL404439 | 0.86 | CD44 (1.00) | CD44CYP3A4TSHRMAPK1ALDH1A1 | |
| SCHEMBL8341703 | 0.83 | CD44 (0.75) | CD44CYP3A4TSHRMAPK1ALDH1A1 | |
| SCHEMBL2026149 | 0.83 | GAA (0.67) | CD44CYP3A4TSHRMAPK1ALDH1A1 | |
| SCHEMBL29683620 | 0.83 | GAA (0.67) | CD44CYP3A4TSHRMAPK1ALDH1A1 | |
| SCHEMBL434710 | 0.83 | GAA (0.58) | CD44CYP3A4TSHRMAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7676240 | 0.83 | CD44 (0.94) | CD44CYP3A4TSHRMAPK1ALDH1A1 | |
| SCHEMBL943759 | 0.83 | CD44 (0.75) | CD44CYP3A4TSHRMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119707773-A | Preparation method and application of maleimide structure-containing compound | 中国农业大学 | 2025-03-28 | — | — | CN | claimed |
| CN-204569782-U | Chloro-2, the 5-xylidine production system filtration units of a kind of 4- | DAMING MINGDING CHEMICAL CO LTD | 2015-08-19 | — | — | CN | claimed |
| CN-116554126-B | Compound for targeted degradation of CDK6 and application thereof | 兰州大学 | 2025-04-18 | — | — | CN | disclosed |
| CN-119707773-A | Preparation method and application of maleimide structure-containing compound | 中国农业大学 | 2025-03-28 | — | — | CN | disclosed |
| CN-119255992-A | Heterocyclic derivatives, compositions and uses thereof | 北京丹擎医药科技有限公司 | 2025-01-03 | — | — | CN | disclosed |
| EP-3957627-B1 | 6-MEMBERED HETEROCYCLIC DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | SHIONOGI & CO (JP) | 2024-06-19 | — | — | EP | disclosed |
| US-20240059703-A1 | HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE | AMGEN INC. | 2024-02-22 | — | — | US | disclosed |
| WO-2023226964-A1 | HETEROCYCLIC DERIVATIVES, COMPOSITIONS AND USES THEREOF | DANATLAS PHARMACEUTICALS CO., LTD. (CN) | 2023-11-30 | — | — | WO | disclosed |
| EP-4232444-A1 | HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE | Amgen Inc. (US) | 2023-08-30 | — | — | EP | disclosed |
| CN-116554126-A | Compound for targeted degradation of CDK6 and application thereof | 兰州大学 | 2023-08-08 | — | — | CN | disclosed |
| WO-2023285222-A1 | HERBICIDAL PHENYLURACILS | BASF SE (DE) | 2023-01-19 | — | — | WO | disclosed |
| EP-0211326-A2 | Production of gravure inks for illustrations | BAYER AG (DE) | 1987-02-25 | — | — | EP | disclosed |
| EP-0168343-A2 | Metal complexes, process for their preparation and their use in dyeing high-molecular organic materials | CIBA-GEIGY AG (CH) | 1986-01-15 | — | — | EP | disclosed |
| US-4421601-A | LACQUERS, INKS, PAINTS, TEXTILES, PAPER | BAYER AKTIENGESELLSCHAFT (DE) | 1983-12-20 | — | — | US | disclosed |
| EP-0056475-A2 | Pharmaceutical compositions | MERCK PATENT GmbH (DE) | 1982-07-28 | — | — | EP | disclosed |
| US-4233055-A | Quaternary ammonioalkanecarboxylic acid anilides as plant growth influencing agents | CIBA-GEIGY CORPORATION (US) | 1980-11-11 | — | — | US | disclosed |
| US-4173645-A | INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-11-06 | — | — | US | disclosed |
| US-4163059-A | Pesticidally active 4,5-dichloro-3-substituted-phenylimino-1,2-dithiolenes | BAYER AKTIENGESELLSCHAFT (DE) | 1979-07-31 | — | — | US | disclosed |
| US-4148799-A | Process for the preparation of 2-aryliminothiazoline solutions | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-10 | — | — | US | disclosed |
| US-4141718-A | ANTIGROWTH AGENTS FOR PLANTS | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240059703-A1 | HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE | KRAS, HRAS, APC | CD44 2696/4885CYP3A4 3478/4885TSHR 4163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.