Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 16/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27598638 | 0.85 | ACACB (0.48) | ALDH1A1POLBAKR1C3AKR1C2 | |
| SCHEMBL1508434 | 0.81 | FFAR1 (0.42) | FFAR1PPARG | |
| SCHEMBL4339997 | 0.79 | FFAR1 (0.42) | FFAR1PPARGALDH1A1SMN1; SMN2AKR1C3 | |
| SCHEMBL2275392 | 0.79 | FFAR1 (0.58) | FFAR1ALDH1A1POLBCYP2C9CYP2C19 | |
| SCHEMBL1508525 | 0.79 | FFAR1 (0.74) | FFAR1PPARG | |
| SCHEMBL4328033 | 0.78 | FFAR1 (0.41) | FFAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13264702 | 0.76 | FFAR1 (0.71) | FFAR1ALDH1A1POLBCYP2C9CYP2C19 | |
| SCHEMBL5720965 | 0.76 | ALDH1A1 (0.51) | FFAR1ALDH1A1POLBCYP2C9CYP2C19 | |
| SCHEMBL5720967 | 0.76 | ALDH1A1 (0.51) | FFAR1ALDH1A1POLBCYP2C9CYP2C19 | |
| SCHEMBL2222589 | 0.74 | POLB (0.53) | FFAR1ALDH1A1POLBCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |