Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2947981 | 0.87 | SMN1; SMN2 (0.74) | FFAR1SMN1; SMN2ALDH1A1CYP2C19POLB | |
| SCHEMBL2948148 | 0.87 | FFAR1 (0.68) | FFAR1SMN1; SMN2ALDH1A1POLBLTA4H | |
| SCHEMBL2949713 | 0.84 | FFAR1 (0.77) | FFAR1SMN1; SMN2ALDH1A1POLBL3MBTL1 | |
| SCHEMBL2941508 | 0.84 | MMP9 (0.65) | FFAR1SMN1; SMN2ALDH1A1POLBLTA4H | |
| SCHEMBL2949131 | 0.83 | MMP9 (0.67) | FFAR1SMN1; SMN2POLBLTA4HL3MBTL1 | |
| SCHEMBL13236731 | 0.83 | FFAR1 (1.00) | FFAR1SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL2946513 | 0.83 | FFAR1 (1.00) | FFAR1SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL2939695 | 0.83 | MMP9 (0.67) | FFAR1SMN1; SMN2POLBLTA4HL3MBTL1 | |
| SCHEMBL13236734 | 0.83 | FFAR1 (1.00) | FFAR1SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL28489153 | 0.83 | FFAR1 (0.61) | FFAR1CNR2CYP2C9CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197036-B | Method for performing anti-mahalanobis hydrogen carboxylation reaction on photocatalytic olefin compound and carbon dioxide | 中国科学院理化技术研究所 | 2024-01-23 | — | — | CN | disclosed |
| CN-115197036-A | Method for carrying out anti-Ma hydrocarboxylation reaction on olefin compound and carbon dioxide by photocatalysis | 中国科学院理化技术研究所 | 2022-10-18 | — | — | CN | disclosed |
| US-7750048-B2 | GPR40 agonists | JANSSEN PHARMACEUTICA NV (BE) | 2010-07-06 | — | — | US | disclosed |
| US-20080176912-A1 | GPR40 AGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176912-A1 | GPR40 AGONISTS | GPR119, GPR65, GPR55 | FFAR1 8/4885SMN1; SMN2 3652/4885CNR2 255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.