SCHEMBL4347462

SCHEMBL4347462

COC(=O)C[Si](OC)(OC)OC

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.48
HSD17B10 Q99714 3/20 0.43
MGAM O43451 2/20 0.43
GAA P10253 2/20 0.43
SI P14410 2/20 0.43
MGAM2 Q2M2H8 2/20 0.43
KMT2A Q03164 2/20 0.36
TET2 Q6N021 1/20 0.36
MEN1 O00255 1/20 0.36
LMNA P02545 3/20 0.34
CA12 O43570 1/20 0.34
CA14 Q9ULX7 1/20 0.34
KDM4E B2RXH2 1/20 0.34
RECQL P46063 1/20 0.34
ALDH1A1 P00352 3/20 0.33
HTT P42858 2/20 0.33
MAPT P10636 1/20 0.33
HSP90AB1 P08238 1/20 0.32
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3910536 0.79 GAA (0.52) HSD17B10MGAMGAASIMGAM2
SCHEMBL3912265 0.77 TSHR (0.42) TSHRHSD17B10MGAMGAASI
SCHEMBL28289105 0.77 ALDH1A1 (0.41) TSHRHSD17B10MGAMGAASI
SCHEMBL10946037 0.76 ALDH1A1 (0.38) TSHRHSD17B10MGAMGAASI
SCHEMBL3919522 0.76 TSHR (0.46) TSHRHSD17B10MGAMGAASI
SCHEMBL29233321 0.75 NAAA (0.39) TSHRHSD17B10LMNAKDM4EALDH1A1
SCHEMBL21271556 0.75 DGAT1 (0.37) CA12CA14KDM4EALDH1A1
SCHEMBL1448792 0.74 FFAR3 (0.35) TSHRLMNAALDH1A1
SCHEMBL990791 0.74
SCHEMBL28378626 0.74 MGAM (0.39) TSHRMGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113150767-B For CO 2 Proppant of fracturing fluid system and modification method and application thereof 中国石油大学(华东) 2023-04-18 CN claimed
CN-113150767-A For CO2Proppant of fracturing fluid system and modification method and application thereof 中国石油大学(华东) 2021-07-23 CN claimed
CN-113150767-B For CO 2 Proppant of fracturing fluid system and modification method and application thereof 中国石油大学(华东) 2023-04-18 CN disclosed
CN-113150767-A For CO2Proppant of fracturing fluid system and modification method and application thereof 中国石油大学(华东) 2021-07-23 CN disclosed
US-20160348488-A1 METHODS OF EXTRACTING HYDROCARBONS FROM SUBTERRANEAN FORMATIONS BAKER HUGHES INCORPORATED 2016-12-01 US disclosed
US-20090277559-A1 METHOD FOR VULCANIZATION-ADHERING RUBBER COMPOSITION TO ADHERENT OF BRASS OR PLATED WITH BRASS, REINFORCING MEMBER FOR RUBBER ARTICLE, RUBBER-REINFORCING MEMBER COMPOSITE AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2009-11-12 US disclosed
EP-1840158-A1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE Bridgestone Corporation (JP) 2007-10-03 EP disclosed